Clinical and Experimental Allergy

VOLUME 29, SUPPLEMENT 1, MARCH 1999

Contents

1 S. T. HOLGATE
Introduction

3 F. E. R. SIMONS
Mizolastine: antihistaminic activity from preclinical data to clinical evaluation

9 B. B. VARGAFTIG
What can we learn from murine models of asthma?

15 Y.G.YAP&A.J.CAMM
The current cardiac safety situation with antihistamines

25 J. BOUSQUET
Rapid symptom relief in rhinitis

31 J.RING
Antihistamines in urticaria

_______________________________________

Clinical and Experimental Allergy

VOLUME 29, NUMBER 2, FEBRUARY 1999

Contents

Editorials:

143 U. WAHN
Do asthmatic children benefit from specific immunotherapy?

144 A. CUSTOVIC & A. WOODCOCK
Feather or synthetic? That is the question

148 P. T. C. HARRISON
Creature comforts - living with mites and moulds

150 M. T. KRISHNA & S. T. HOLGATE
Inflammatory mechanisms underlying potentiation of effects
of inhaled aeroallergens in response to nitrogen dioxide in
allergic airways disease

155 R. C. BENYON
Mast cells in the liver

Reviews:

159 M. S. DE BRUIN-WELLER, F. R. WELLER &
J. G. R. DE MONCHY
Repeated allergen challenge as a new research model for studying
allergic reactions

166 J. E. CALVERT, C. 1. BALDWIN, A. ALLEN, A. TODD &
S.J.BOURKE
Pigeon fanciers' lung: a complex disease?

Original articles:

176 W. GRUBER, E. EBER, P. MILEDER, M. MODL,
E. WEINHANDL & M. S. ZACH
Effect of specific immunotherapy with house dust mite extract
on the bronchial responsiveness of paediatric asthma patients
182 N. RAINS, R. SIEBERS, J. CRANE & P. FITZHARRIS
House dust mite allergen (Der p 1) accumulation on new
synthetic and feather pillows

186 Y. KATZ, H. VERLEGER, J. BARR, M. RACHMIEL,
S. KIVITI & E. S. KUTTIN
Indoor survey of moulds and prevalence of mould atopy
in Israel

193 F. CARSWELL, J. OLIVER & J. WEEKS
Do mite avoidance measures affect mite and cat airborne
allergens?

201 F. T. CHEW, L. ZHANG, T. M. HO & B. W. LEE
House dust mite fauna of tropical Singapore

207 T. JUNG, K. WITZAK, K. DIECKHOFF, K. ZACHMANN,

S. HEIDRICH, G. AVERSA & C. NEUMANN
IFN-gamma is only partially restored by co-stimulation with IL-12,
IL-2, IL-15, IL-18 or engagement of CD28

217 M. J. VAN DER VEEN, R. J. J. VAN NEERVEN,
E. C. DE JONG, R. R. C. AALBERSE, H. M. JANSEN &
J. S. VAN DER ZEE
The late asthmatic response is associated with baseline allergen-
specific proliferative responsiveness of peripheral T lymphocytes
in vitro and serum interleukin-5

228 E.NOGUCHI,M.SHIBASAKI,T.ARINAMI,K.TAKEDA,

Y. YOKOUCHI, K. KOBAYASHI, N. IMOTO,
S. NAKAHARA, A. MATSUI & H. HAMAGUCHI
Lack of association of atopy/asthma and the interleukin-4
receptor alpha gene in Japanese

234 J. H. WANG, J. L. DEVALIA, C. RUSZNAK, A. BAGNALL,

R. J. SAPSFORD & R. J. DAVIES
Effect of fluticasone propionate aqueous nasal spray on allergen-
induced inflammatory changes in the nasal airways of allergic
rhinitics following exposure to nitrogen dioxide

241 H. K. MAKKER, D. R. SPRINGALL, A. E. REDINGTON,
M. A. GHATEI, S. R. BLOOM, J. M. POLAK, P. H. HOWARTH
& S. T. HOLGATE
Airway endothelin levels in asthma: influence of endobronchial
hypertonic saline challenge

248 R. WARD, G. WOLTMANN, A. J. WARDLAW &
1. D. PAVORD
Between-observer repeatability of sputum differential cell
counts. Influence of cell viability and squamous cell
contamination

253 M. MIYAJIMA, M. SUGA, K. NAKAGAWA, K. ITO &

M. ANDO

Effects of erythromycin on experimental extrinsic allergic
alveolitis

262 A. M. COLLINS, S. LEACH, J. PAYNE, A. MITCHELL,

Y. DAI & G. D. F. JACKSON

A role for the hepatobiliary system in lgE-mediated intestinal
inflammation in the rat

271 L.-F. WANG, C.-C. SUN, J.-T. WU & R.-H. LIN
Epicutaneous administration ofhapten through patch application
augments TH2 responses which can downregulate the elicitation
of murine contact hypersensitivity

Correspondence:

280 M. L. H. FLINDT
Proteinases and sensitization: house mites and enzyme detergents

281 C. ROBINSON, H. WAN & H. 1. WINTON
Response

282 G. L. PIACENTINI & A. L. BONER
Response

284 Forthcoming meetings

285 Forthcoming articles

_______________________________________

Clinical and Experimental Allergy

VOLUME 29, NUMBER 3, MARCH 1999

Contents

Editorials:

287 L. M. TERAN

Chemokines and IL-5: major players ofeosinophil recruitment
in asthma

291 S. 0. SHAHEEN
Obesity and asthma: cause for concern?

294 J.CORNE

Do inhaled corticosteroids reduce serum lgE levels? The answer
is maybe but how relevant is the question?

Reviews:

298 V. WESTERGREN

Artificial ventilation-acquired sinopathy in the critically ill—the
maxillary sinuses revisited

306 M.SANAK& A. P. SAMPSON
Biosynthesis ofcysteinyl-leucotrienes in aspirin-intolerant asthma

Original articles:

314 M. LAMPINEN, S. RAK & P. VENGE
The role ofinterleukin-5, interleukin-8 and RANTES in the
chemotactic attraction of eosinophils to the allergic lung
323 S.-L. HUANG, G.-M. SHIAO & P. CHOU
Association between body mass index and allergy in teenage
girls in Taiwan

330 A. GREGORY, 1. DOULL, N. PEARCE, S. CHENG,
P. LEADBITTER, S. HOLGATE & R. BEASLEY
The relationship between anthropornetric measurements at birth:
asthma and atopy in childhood

334 M.-P ORYSZCZYN, 1. ANNESI-MAESANO, D. CAMPAGNA,
J. SAHUQUILLO, G. HUEL & F. KAUFFMANN
Head circumference at birth and maternal factors related to cord
blood total lgE

342 B. BJORKSTEN, P. NAABER, E. SEPP & M. MIKELSAAR
The intestinal microflora in allergic Estonian and Swedish
2-year-old children

347 J. EMBERLIN, J. MULLINS, J. CORDEN, S. JONES,
W. MILLINGTON, M. BROOKE & M. SAVAGE
Regional variations in grass pollen seasons in the UK, long-term
trends and forecast models

357 T. OHRUI, T. FUNAYAMA, K. SEKIZAWA, M. YAMAYA &
H. SASAKI

Effects of inhaled beclomethasone dipropionate on serum lgE
levels and clinical symptoms in atopic asthma

362 M.ENNIS.G. TURNER, B.C.SCHOCK, E.C.STEVENSON,
V. BROWN, P. S. FITCH, L. G. HEANEY, R. TAYLOR &
M. D. SHIELDS
Inflammatory mediators in bronchoalveolar lavage samples from
childre i with and without asthma
367 L.KLIMEK&G.RASP

Norm values for eosinophil cationic protein in nasal secretions:
influence of specimen collection

375 C. 1. EZEAMUZm, S. F. AL-ALI, A. AL-DOWAISAN,
M. KHAN, Z. HIAZI & M. S. THOMSON
Reference values of total serum lgE and their significance in the
diagnosis of allergy among the young adult Kuwaiti population
382 Z. SZ^PFALUSI, L. TODORAN, S. ELSASSER, B. JAGDT,

H. WANK & R. URBANEK
Cord blood leucocytes/basophils produce and release
sulfidoleucotrienes in response to allergen stimulation
388 F. MORELL, R. CODINA & M.-J. RODRIGO
Increased positivity of skin test and allergenic stability of
glycerinated soybean hull extracts

394 A. KETTNER.H. HENRY, G.J.HUGHES,G.CORRADIN&
F. SPERTINI

lgE and T-cell responses to high-molecular weight allergens from
bee venom

402 A. FIOCCHI, P. RESTANI, M. TRAVAINI, E. DECET,
A. GAIASCHI, L. BERNARDO & E. RIVA
Carob is not allergenic in peanut-allergic subjects
407 A. CURIONI, B. SANTUCCI, A. CRISTAUDO,
C. CANISTRACI, M. PIETRAVALLE, B. SIMONATO &
M. GIANNATTASIO

Urticaria from beer: an immediate hypersensitivity reaction due
to a IO-kDa protein derived from barley

414 C K. YU, B. C. YANG, H. Y. LEI, Y. C. CHEN, Y.-H. LIU,

C. C. CHEN & C.-W. LIU

Attenuation of house dust mite Dermatophagoidesfarinae-
induced airway allergic responses in mice by
dehydroepiandrosterone is correlated with down-regulation of
TH2 response

Correspondence:
423
D.HEEDERIK&G.DOEKES
Exposure-response relationships for airborne allergens

425 Book reviews

426 Forthcoming meetings

427 Forthcoming articles

_______________________________________

Clinical and Experimental Allergy

VOLUME 29, NUMBER 4, APRIL 1999

Contents

Editorials:

429 P. FITZHARRIS, R. SIEBERS & J. CRANE
Pillow talk: have we made the wrong beds for our patients to
lie in?

433 B. BRUNEKREEF
On carpets, construction and covers

436 J. D. A. MACLEOD

The treatment of allergic eye disease: has sodium cromoglycate
had its day?

Reviews:

439 0. SCHULZ, H. F. SEWELL & F. SHAKIB
The interaction between the dust mite antigen Der p I and cell-
signalling molecules in amplifying allergic disease

445 V. H. J. VAN DER VELDEN & A. R. HULSMANN
Peptidases: structure, function and modulation of peptide-
mediated effects in the human lung

Original articles:

457 A. C. FROSH, G. SANDHU, R. JOYCE & D. P. STRACHAN
Prevalence of rhinitis, pillow type and past and present ownership
of furred pets

461 S. DHARMAGE, M. BAILEY, J. RAVEN, A. CHENG,
J. ROLLAND, F. THIEN, A. FORBES, M. ABRAMSON &
E. H. WALTERS

Residential characteristics influence Der p I levels in homes in
Melbourne, Australia

470 G. L. CHEW, K. M. HIGGINS, D. K. MILTON & H. A. BURGE
The effects of carpet fresheners and other additives on the
behaviour of indoor allergen assays

478 R. FRIEDL-HAJEK, M. D. SPANGFORT, C. SCHOU,
H. BREITENEDER, H. YSSEL & R. J. JOOST VAN NEERVEN
Identification of a highly promiscuous and an HLA allele-specific
T-cell epitope in the birch major allergen Bet v 1: HLA restriction,
epitope mapping and TCR sequence comparisons

488 Z.-N. CHANG, H.-J. PENG, W.-C. LEE, T.-S. CHEN,
K.-Y, CHUA, L.-C. TSAI, C.-W« CHI & S.-H. HAN
Sequence polymorphism of the group I allergen of Bermuda
grass pollen

497 K. GEHLHAR, M. SCHLAAK, W.-M. BECKER & A. BUFE
Monitoring allergen immunotherapy of pollen-allergic patients:
the ratio of allergen-specific lgG4 to lgGI correlates with clinical
outcome

507 S. H. SICHERER & H. A. SAMPSON
Cow's milk protein-specific lgE concentrations in two age groups
of milk-allergic children and in children achieving clinical
tolerance

513 A. WISTOKAT-WOLFING, P. SCHMIDT, U. DARSOW,

J. RING, A. KAPP & T. WERFEL
Atopy patch test reactions are associated with T lymphocyte-
mediated allergen-specific immune responses in atopic dermatitis

522 L. VON HERTZEN, M. TOYRYLA, A. GIMISHANOV,
A. BLOIGU, M. LEINONEN, P. SAIKKU & T. HAAHTELA
Asthma, atopy and Chlamydia pneumoniae antibodies in adults

529 P. H. VERIN, 1. D. DICKER & B. MORTEMOUSQUE
Nedocromil sodium eye drops are more effective than sodium
cromoglycate eye drops for the long-term management of vernal
keratoconjunctivitis

537 M. VESALUOMA, M. E. ROSENBERG, A.-M. TEPPO,
C. GRONHAGEN-RISKA, T. HAAHTELA & T. TERVO
Tumour necrosis factor alpha (TNF(x) in tears of atopic patients
after conjunctival allergen challenge

543 H.-S. PARK, K.-S. JUNG, K.-R. KANG, D.-H. NAHM,
S.-H. CHO & Y.-Y. KIM

Enhanced basophil histamine release and neutrophil chemotactic
activity predispose grain dust-induced airway obstruction

550 M. NAGATA, J. B. SEDGWICK, R. VRTIS & W. W. BUSSE
Endothelial cells upregulate eosinophil superoxide generation
viaVCAM-l expression

562 G. L. HALL, F. PET^K, C. McMENAMIN & P. D. SLY
The route of antigen delivery determines the airway and lung
tissue mechanical responses in allergic rats

569 Forthcoming meetings

570 Forthcoming articles

_______________________________________

Clinical and Experimental Allergy

VOL.29, NO.5, MAY 1999

573 P.M.O'BYRNE&L.WOOD

lnterleukin-5 and allergic inflammation
576 S. H. ARSHAD & Y NANABHAY
Early biomarkers of allergic disease in children

Reviews:

579 C. ADVENIER, G. JOOS, M. MOLIMARD, V. LAGENTE <S

R. PAUWELS

Role of tachykinins as contractile agonists of human airways
in asthma

585 1. SAVERS & B. A. HELM
The structural basis of human lgE-Fc receptor interactions

Original articles:
595 G. HALLDEN, C. HELLMAN, R. GRONNEBERG &

J. LUNDAHL

Increased levels of IL-5 positive peripheral blood eosinophils
and lymphocytes in mild asthmatics after allergen inhalation
provocation

604 P. E. D. EYSINK, M. H. DE JONG, R J. E. BINDELS,
V. T. M. SCHARP-VAN DER LINDEN, C. J. DE GROOT,
S. 0. STAPEL & R. C. AALBERSE

Relation between lgG antibodies to foods and lgE antibodies
to milk, egg, cat, dog and/or mite in a cross-sectional study
611 B. HESSELMAR, N. ABERG, B. ABERG, B. ERIKSSON &

B. BJORKSTEN

Does early exposure to cat or dog protect against later allergy
development?

618 N. MEISSNER, S. KOCHS, J. COUTELLE, F. KUSSEBI,
C. BAUMGARTEN, H. L0WENSTEIN, G. KUNKEL &
H. RENZ

Modified T-cell activation pattern during specific immunotherapy
(SIT) in cat-allergic patients

626 M. WICKMAN, A.-C. EGMAR, G. EMENIUS, C. ALMQVIST,
N. BERGLIND, P. LARSSON & M. VAN HAGE-HAMSTEN
Pel d I and Can f I in settled dust and airborne Pel d I in
allergen avoidance day-care centres for atopic children in relation
to number of pet-owners, ventilation and general cleaning
633 G. F. SCHAPPI, P E. TAYLOR, M. C. F. PAIN, P. A. CAMERON,
A. W. DENT, 1. A. STAFF & C. SUPHIOGLU
Concentrations of major grass group 5 allergens in pollen grains
and atmospheric particles: implications for hay fever and allergic
asthma sufferers sensitized to grass pollen allergens
642 H.-D. SHEN, W.-L. LIN, M. F. TAM, S.-R. WANG,

S.-S. TZEAN, M.-H. HUANG & S.-H. HAN
Characterization of allergens from Penicillium oxalicum and
P. notatum by immunoblotting and N-terminal amino acid
sequence analysis

652 L. M. VANDEZANDE, B. WALLAERT, P. DESREUMAUX,

A. TSICOPOULOS, C. LAMBLIN, A. B. TONNEL &
A. JANIN

lnterleukin-5 immunoreactivity and mRNA expression in gut
mucosa from patients with food allergy

Triformatinn nn this inurnal ran hf* nccpWt

660 E. LOUIS, R. LOUIS, J. SHUTE, L. LAU, D. FRANCHIMONT,
A. LAMPROYE, M. RADERMECKER, R. DJUKANOVIC
& J. BELAICHE

Bronchial eosinophilic infiltration in Crohn's disease in the
absence of pulmonary disease

667 A. POSCH, C. H. WHEELER, Z. CHEN, A. FLAGGE,
M. J. DUNN, F. PAPENFUSS, M. RAULF-HEIMSOTH &
X. BAUR

Class I endochitinase containing a hevein domain is the causative
allergen in latex-associated avocado allergy

673 R. SANCHEZ-MONGE, C. BLANCO, A. DfAZ-PERALES,
C. COLLADA, T. CARRILLO, C. ARAGONCILLO &
G. SALCEDO

Isolation and characterization of major banana allergens:
identification as fruit class I chitinases

681 R. BERNARDINI, E. NOVEMBRE, E. LOMBARDI,
P MEZZETTI, A. CIANFERONI, D. A. DANTI,
A. MERCURELLA & A. VIERUCCI
Risk factors for latex allergy in patients with spina bifida and
latex sensitization

687 T. MATSUYAMA, K. URANO, M. OHKIDO, H. OZAWA,
A. OHTA, S. KANEKO, T. YAHATA, C. TAKITA &
T. NISHIMURA

The quantitative and qualitative defect of CD4^ CD45RO^
memory-type T cells are involved in the abnormality ofTHI
immunity in atopic dermatitis patients

695 M. SCHMELZ, S. ZECK, M. RAITHEL & R. RUKWIED
Mast cell tryptase in dermal neurogenic inflammation

703 A. E. CALVERLEY, D. REES & R. J. DOWDESWELL
Allergy to complex salts of platinum in refinery workers:
prospective evaluations of lgE and Phadiatop® status

712 S. CIANCHETTI, E. BACCI, L. RUOCCO, M. L. BARTOLI,
S. CARNEVALI, F. L. DENTE, A. Dl FRANCO, D. GIANNINI,
L. SCUOTRI, B. VAGAGGINI & P. L. PAGGIARO
Salbutamol pretreatment does not change eosinophil percentage
and eosinophilic cationic protein concentration in hypertonic
saline-induced sputum in asthmatic subjects

Correspondence:
719 L M. BALFOUR-LYNN
Quantitative evaluation of nasal mucus proteins

719 B.FATTORI
Response

720 Erratum

722 Forthcoming meetings

723 Forthcoming articles

_______________________________________


Clinical and Experimental Allergy
VOLUME 29, NUMBER 6, JUNE 1999


Editorials:
725 B. J. BATEMAN & T. P. DEAN
The Cheshire cal's grin — is cat allergy here to stay?

729 J. MATTES & W. KARMAUS
The use of antibiotics in the first year of life and development
of asthma: which comes first?

733 J. M. HOPKIN
Early life receipt of antibiotics and atopic disorder

735 M. L. BURR
Grass pollen: trends and predictions

Special article — debate of the age:

739 L. DOW
Asthma versus chronic obstructive pulmonary disease —
exploring why 'reversibility versus irreversibility' is no longer
an appropriate approach

Reviews:

744 B. A. BALDO
Penicillins and cephalosporins as allergens — structural aspects
of recognition and cross-reactions

750 D. J. ROSS
Ten years of the SWORD project

Original articles:

754 K. ICHIKAWA, E. IWASAKI, M. BABA & M. D. CHAPMAN
High prevalence ofsensitization to cat allergen among Japanese
children with asthma, living without cats

762 M. CHAN-YEUNG, P. A. McCLEAN, P. R. SANDELL,
A. S. SLUTS KY & N. ZAMEL
Sensitization to cat without direct exposure to cats

766 K. WICKENS, N. PEARCE, J. CRANE & R. BEASLEY
Antibiotic use in early childhood and the development of asthma

772 P. BORGER, N. H. T. TEN HACKEN, E. VELLENGA.
H. F. KAUEFMAN & D. S. POSTMA
Peripheral blood T lymphocytes from asthmatic patients are
primed for enhanced expression of interleukin (IL)-4 and IL-5
mRNA: associations with lung function and serum lgE

780 T. NOMA, M. HAYASHI, Y. KAWANO, 1. YOSHIZAWA,
Y. ISHIKAWA, T. SAEKI, K. AOKI & N. MATSUURA
Functional interleukin-5 activity in peripheral blood mononuclear
cells from adolescents with mite antigen asthma in remission

786 D. Y. KOLLER, G. HALMERBAUER, T. FRISCHER &
B. ROITHNER
Assessment ofeosinopliil granule proteins in various body fluids:
is there a relation to clinical variables in childhood asthma?

794 K. A. DEICHMANN, A. SCHMIDT, A. HEINZMANN,
S. KRUSE, J. FÖRSTER & J. KUEHR
Association studies on P^-adrenoceptor polymorphisms and
enhanced lgE responsiveness in an atopic population

800 K. TANAKA, H. SUGIURA, M. UEHARA, H. SATO,
T. HASHIMOTO-TAMAOKI & J. FURUYAMA
Association between mast cell chymase genotype and atopic
eczema: comparison between patients with atopic eczema alone
and those with atopic eczema and atopic respiratory disease

804 P. BERGER, S. J. COMPTON, M. MOLIMARD, A. F. WALLS,
C. N'GUYEN, R. MARTHAN & J. M. TUNON-DE-LARA
Mast cell tryptase as a mediator of hyperresponsiveness in
human isolated bronchi

813 V. H. J. VAN DER VELDEN, B. A. E. NAB ER,
P. TH. W. VAN HAL, S. E. OVERBEEK, H. C. HOOGSTEDEN
& M. A. VERSNEL
Peptidase activities in senim and bronchoalveolar lavage fluid
from allergic asthmatics — comparison with health non-smokers
and smokers and effects of inhaled glucocorticoids

824 J. SAVOLAINEN, J. KOSONEN, P. LINTU, M. VIANDER,
J. PENE, K. KALIMO, E. 0. TERHO & J. BOUSQUET
Candida albicans mannan- and protein-induced humoral, cellular
and cytokine responses in atopic dermatitis patients

832 A. MICHILS. l. VERVIER, G. CHOUFANI, B. GOSSART &
J. DUCHATEAU
Relationship between allergic status and specificity ofIgG
antibody to inhaled allergens: the grass pollen model

840 K. HOFFMANN-SOMMERGRUBER, G. O'RIORDAIN,
H. AHORN, C. EBNER,
M. LAIMER DA CAMARA MACHADO, H. PÜHRINGER,
O. SCHEINER & H. BREITENEDER
Molecular characterization of Dau c I, the Bet v I homologous
protein from carrot and its cross-reactivity with Bet v I and
Api g 1

848 R. VAN REE, W. A. VAN LEEUWEN, J. H. AKKERDAAS &
R. C. AALBERSE
How far can we simplify in vitro diagnostics for Fagales tree
pollen allergy? A study with three whole pollen extracts and
purified natural and recombinant allergens

856 C. KOBAYASHI, H. NIGI, S. SAITO, T. IDE, Y. TANIGUCHI,
S. INOUYE & M. SAKAGUCHI
lgE reactivity and cross-reactivity of Japanese monkeys (Macaco
fitsca(a) to Japanese cedar (Cryptomeriajaponica) and cypress
(Chamaecyparis obtusa) pollen allergens

862 Forthcoming meetings

863 Forthcoming articles

864 Erratum
________________________________

 

Clinical and Experimental Allergy
VOLUME 29, NUMBER 7, JULY 1999

Editorials:
865 C.A.JONES&J.O.WARNER
Regulating a regulator: IFNy production by the neonate

869 P.S.FRIEDMANN
The role of dust mite antigen sensitization and atopic dermatitis

873 M.O.HOEKSTRA
Can eosinophil-derived proteins be used to diagnose or to monitor
childhood asthma?

Reviews

875 E.L.BECKER
Elements of the history of our present concepts of anaphylaxis,
hay fever and asthma

896 R. VALENTA, J. LIDHOLM, V. NIEDERBERGER, B. HAYEK,
D. KRAFT & H. GRONLUND
The recombinant allergen-based concept of component-resolved
diagnostics and immunotherapy (CRD and CRIT)

Original articles:

905 D.SHERRILL,R. STEIN, M.KURZIUS-SPENCER&
F. MARTINEZ
On early sensitization to allergens and development of respiratory
symptoms

912 T. JUNG, R. MOESSNER, K. DIECKHOFF, S. HEIDRICH &
C. NEUMANN
Mechanisms of deficient interferon-y production in atopic
diseases

920 C.GUTGESELL,A.SEUBERT,V.JUNGHANS&
CH. NEUMANN
Inverse correlation of domestic exposure to Dermatophagoides
pteronyssinus antigen patch test reactivity in patients with atopic
dermatitis

926 C. WOJNAROWSKI, B. ROITHNER, D. Y. KOLLER,
G. HALMERBAUER, C. GARTNER, E. TAUBER &
T. FRISCHER
Lack of relationship between eosinophil cationic protein and
eosinophil protein X in nasal lavage and urine and the severity
of childhood asthma in a 6-month follow-up study

933 P. BORGER, G.-J. JONKER, E. VELLENGA, D. S. POSTMA,
J. G. R. DE MONCHY & H. F, KAUFFMAN
Allergen challenge primes for IL-5 mRNA production and
abrogates p-adrenergic function in peripheral blood T lymphocytes
from asthmatics

941 A.MIADONNA,N.MILAZZO,S.GIBELLI,C.SALMASO,
M. LORINI & A. TEDESCHI
Nasal response to a single antigen challenge in patients with
allergic rhinitis — inflammatory cell recruitment persists up to
48 hours

950 T. SHOJI, S. YOSHIDA, H. SAKAMOTO, H. HASEGAWA,
H. NAKAGAWA & H. AMAYASU
Anti-inflammatory effect of roxithromycin in patients with
aspirin -intolerant asthma

957 C.McSHARRY,K.MacLEOD,S.McGREGOR,
A. B. J. SPEEKENBRINK, S. SRIRAM, F. BOYD &
G. BOYD
Mucosal immunity in extrinsic allergic alveolitis: salivary
immunoglobulins and antibody against inhaled avian antigens
among pigeon breeders

965 D. K. PETKOVA, L. PANG, S. P. RANGE, E. HOLLAND &
A. J. KNOX
Immunocytochemical localization of cyclo-oxygenase isoforms
in cultured human airway structural cells

973 U.LOVBORG, P. J. BAKER, D.J.M.TAYLOR, P. YIN&
E. R. TOVEY
Subtribe-specific monoclonal antibodies to Lolium perenne

982 F.T. CHEW, F.C.YI.K.YCHUA.E.FERNANDEZ-CALDAS,
L. K. ARRUDA, M. D. CHAPMAN & B. W. LEE
Allergenic differences between the domestic mites Blomia
tropicalis and Dermatophagoides pteronyssinus

989 J. KAUPPINEN, T. ZEILER, J. RAUTIAINEN,
M. RYTKONEN-NISSINEN, A. TAIVAINEN,
R. MANTYJARVI & T. VIRTANEN
Mutant derivatives of the main respiratory allergen of cow are
less allergenic than the intact molecule

997 P. RESTANI, A. GAIASCHI, A. PLEBANI, B. BERETTA,
G. CAVAGNI, A. FIOCCHI, C. POIESI, T. VELONA,
A. G. UGAZIO & C. L. GALLI
Cross-reactivity between milk proteins from different animal
species

1005 Forthcoming meetings

1006 Forthcoming articles

_________________________________________


Clinical and Experimental Allergy
VOLUME 29, NUMBER 8, AUGUST 1999

Editorials:
1009 A. J. CHAÜHAN
Gas cooking appliances and indoor pollution

1014 A. CARROCCIO, F. CAVATAIO & G. IACONO
Cross-reactivity between milk proteins of different animals

1017 R.MOQBEL&P.LACY
Exocytotic events in eosinophils and mast cells

Review:

1023 J. W. HOLLOWAY, B. BEGHE & S. T. HOLGATE
The genetic basis of atopic asthma

Original articles:

1033 S. E. MORAN, D. P. STRACHAN, I. D. A. JOHNSTON &
H. R. ANDERSON
Effects of exposure to gas cooking in childhood and adulthood
on respiratory symptoms, allergic sensitization and lung
function in young British adults

1042 S. M. TARIQ, S. H. ARSHAD, S. M. MATTHEWS &
E. A. HAKIM
Elevated cord serum lgE increases the risk of aeroallergen
sensitization without increasing respiratory allergic symptoms
in early childhood

1049 V. STEPHAN, J. KUEHR, A. SEIBT, H. SAUERESSIG,
S. ZINGSEM, T. D. DINH, M. MOSELER, V. WAHN &
K. A. DEICHMANN
Genetic linkage of HLA-class II locus to mite-specific lgE
immune responsiveness

1055 I. SELO, G. CLEMENT, H. BERNARD, J.-M. CHATEL,
C. CREMINON, G. PELTRE & J.-M. WAL
Allergy to bovine p-lactoglobulin: specificity of human lgE
to tryptic peptides

1064 A. ÜMPIERREZ, S. QÜL "E, F. MARANÖN, J. CUESTA,
Y. GARCfA-VILLAMUZA, C. LAHOZ & J. SASTRE
Allergy to goat and sheep cheese with good tolerance to cow
cheese

1069 J. FERNANDEZ, M. BLANCA, V. SORIANO, J. SANCHEZ
& C. JUAREZ
Epidemiological study of the prevalence of allergic reactions
to Hymenoptera in a rural population in the Mediterranean
area

1075 E. JENSEN-JAROLIM, G. GERSTMAYER, D. KRAFT,
O. SCHEINER, H. EBNER & C. EBNER
Serological characterization of allergens in poppy seeds

1080 J. W. PARK, S. H. KO, C. W. KIM, B.-J. JEOUNG &
C.-S. HONG
Identification and characterization of the major allergen of the
Humulusjaponicus pollen

1087 C. AFFERNI, P. IACOVACCI, B. BARLETTA,
G. Dl FELICE, R. TINGHINO, A. MARI & C. PINI
Role of carbohydrate moieties in lgE binding to allergenic
components of Cupressus arizonica pollen extract

1095 S. LORENZO, R. IGLESIAS, M. T. AUDfCANA,
R. GARCfA-VILLAESCUSA, F. PARDO,
M. L. SANMARTfN & F. M. UBEIRA
Human immunoglobulin isotype profiles produced in response
to antigens recognized by monoclonal antibodies specific to
Anisakis simplex

1102 Y.-Y. KIM, J.-W. SON, H.-Y. KIM, H.-S. PARK, M.-H. LEE,
S.-H. CHO, K.-U. MIN & Y.-Y. KIM
Citrus red mite (Panonychus citri ) is the most common
sensitizing allergen of asthma and rhinitis in citrus farmers

1110 Y. MORISHITA, J. TADA, A. SATO, Y. TOI, H. KANZAKI,
H. AKIYAMA & J. ARATA
Possible influences of Staphylococcus aureus on atopic
dermatitis—the colonizing features and the effects of
staphylococcal enterotoxins

1118 A. M. DVORAK & E. S. MORGAN
Ribonuclease-gold ultrastructural localization of heparin in
isolated human lung mast cells stimulated to undergo
anaphylactic degranulation and recovery in vitro

1129 T. OBATA, T. NAGAKURA, T. MASAKI, K. MAEKAWA
& K. YAMASHITA
Eicosapentaenoic acid inhibits prostaglandin D(2) generation
by inhibiting cyclo-oxygenase-2 in cultured human mast cells

1136 A.-S. JANG, L-S. CHOI, S. LEE, J.-P. SEO. S.-W. YANG,
K.-O. PARK, K.-Y. LEE, J.-Ü. LEE, C.-S. PARK &
H.-S. PARK
Nitric oxide metabolites in induced sputum: a marker of
airway inflammation in asthmatic subjects

1143 F. PURELLO-D'AMBROSlO, S. ISOLA, L. RICCIARDI,
S. GANGEMI, L. BARRESI & G. F. BAGNATO
A controlled study on the effectiveness of loratadine in
combination with flunisolide in the treatment of nonallergic
rhinitis with eosinophilia (NARES)

1148 Forthcoming meetings

1149 Forthcoming articles

_______________________________________


CLINICAL AND EXPERIMENTAL ALLERGY


VOLUME 29, NUMBER 9, SEPTEMBER 1999


Contents

Editorials:

1151 I1. P. HALL
B2-adrenoceptor polymorphisms and asthma

1155 A.J.FREW
Cloning T cells from sites of allergic inflammation

1158 G.SALCEDO,A.DfAZ-PERALES&R.SANCHEZ-MONGE
Fruit allergy: plant defence proteins as novel potential
panallergens


1161 W.J.PICHLER
Anisakiasis: immunity, allergy or both? Lessons on the natural
role of immunoglobulin E from a nematode infestation

Reviews:

1164 M.PRETOLANI
Interleukin-IO: an anti-inflammatory cytokine with therapeutic
potential

1172 P. VENGE, J/BYSTROM, M. CARLSON, L. HAKANSSON,
M. KARAWACJZYK, C. PETERSON, L. SEV^US &
A.TRULSON
Eosinophil cationic protein (ECP): molecular and biological
properties and the use of ECP as a marker of eosinophil
activation in disease

1187 S.SALVI&S.T.HOLGATE
Mechanisms of particulate* matter toxicity

Original articles:

1195 C.E. RAMSAY, C.M.HAYDEN,K.J. TILLER,
P. R. BURTON, J. GOLDBLATT & P. N. LESOUEF
Polymorphisms in the B2-adrenoreceptor gene are associated
With deceased airway responsiveness


1204 T.C.LIKAMWA,A.H.MANSUR,J.BRITTON,
G. WILLIAMS, I. PAVORD, K. RICHARDS,
D. A. CAMPBELL, N. MORTON, S. T. HOLGATE &
J. F. J. MORRISON
Association between - 308 tumour necrosis factor promoter
polymorphism and bronchial hyperreactivity in asthma

1209 H.DAI,J.GUZMAN,P.C.BAUER&U.COSTABEL
Elevated levels of soluble TNF receptors in bronchoalveolar
lavage fluid in extrinsic allergic alveolitis

1214 V. L. CALDER, G. JOLLY, M. HINGORANI, P. ADAMSON,
A. LEONARDI, A. G. SECCHI, R. J. BUCKLEY &
S. LIGHTMAN
Cytokine production and mRNA expression by conjunctival
T-cell lines in chronic allergic eye disease

1223 C.MACAUBAS, P. D. SLY, P. BURTON, K. TILLER,
A. YABUHARA, B. J. HOLT, T. B. SMALLACOMBE,
G. KENDALL, M. C. JENMALM & P. G. HOLT
Regulation ofT-helper cell responses to inhalant allergen
during early childhood

1232 L.M.POULOS,T.J.O'MEARA,R.SPORIK&E.R.TOVEY
Detection of inhaled Der p 1


1239 M.FERNANDEZ-RIVAS&M.CUEVAS
Peels of Rosaceae fruits have a higher allergenicity than pulps

1248 P. CADOT, E. M. VAN HOEYVELD, J. L. CEUPPENS &
E. A. M. STEVENS
Composition and stability of allergenic extracts made from
gamma-irradiated rye grass (Lolium perenne) pollen

1256 R.S.H.PUMPHREY,P.B.WILSON,E.B.FARAGHER&
S. R. EDWARDS
Specific immunoglobulin E to peanut, hazelnut and brazil nut
in 731 patients: similar patterns found at all ages

1260 A. DASCHNER, A. ALONSO-GOMEZ, T. CABALLERO,
J. M. SUAREZ-DE-PARGA & M. C. LOPEZ-SERRANO
Usefulness of early serial measurement of specific and total
immunoglobulin Ein the diagnosis ofgastro-allergic anisakiasis

1265 J. J. GARCfA-GONZALEZ, B. BARTOLOME-ZAVALA,
M. DEL MAR TRIGO-PEREZ, J. M. BARCEL6-MUNOZ,
S. FERNANDEZ-MELENDEZ, M. A. NEGRO-CARRASCO,
M. J. CARMONA-BUENO, J. M. VEGA-CHICOTE,
C. MUNOZ-ROMAN, R. PALACIOS-PELAEZ,
B. CABEZUDO-ARTERO & J. MARTINEZ-QUESADA
Pollinosis to Ricimis communis (castor bean): an
aerobiological, clinical and iininunochcmical study

1276 LHORVATH&RJ.BARNES
Exhaled monoxides in asymptomatic atopic subjects

1281 Y. MUNAKATA, Y UMEZAWA, S. IWATA, R.-P. DONG,
S. YOSHIDA, T. ISHII & C. MORIMOTO
Specific inhibition of TH2-type cytokine production from
human peripheral T cells by terfenadine in vitro

1287 S. R. RUTGERS, G. H. KOETER, T. W. VAN DER MARK
& D. S. POSTMA
Protective effect of oral terfenadine and not inhaled ipratropium
on adenosine 5'-monophosphate-induced bronchoconstriction
in patients with COPD

1293 Forthcoming meetings

1294 Forthcoming articles


_______________________________________


CLINICAL AND EXPERIMENTAL ALLERGY


VOLUME 29, NUMBER 10, OCTOBER 1999

Contents

Editorials:

1295 J.W.WILSON&A.G.STEWART
Airway vascularity in asthma

1298 L.CAMPOROTA&J.W.HOLLOWAY
lnterleukin-12 and allergic tissue response

1301 D.LEZCANO-MEZA&L.M.TERAN
Occupational asthma and interleukin-8

Reviews:

1304 P.A.STEERENBERG,J.G.C.VANASTERDAM,
R. J. VANDEBRIEL, J. G. BOS, L. VAN BREE &
H. VAN LOVEREN
Environmental and lifestyle factors may act in concert to
increase the prevalence of respiratory allergy including asthma

1309 D.E. JAMES &F. P. NIJKAMP
Neuro-immune interactions in the lung

Original articles:

1320 E.D.WRIGHT,P.CHRISTODOULOPOULOS,
S. FRENKIEL & Q. HAMID
Expression ofinterleukin (IL)-12 (p40) and IL-12 (B2) receptors
in allergic rhinitis and chronic sinusitis


1326 L.KLIMEK,D.DORMANN,E.R.JARMAN,
0. CROMWELL, H. RIECHELMANN &
A. B. RESKE-KUNZ
Short-term preseasonal birch pollen allergoid immunotherapy
influences symptoms, specific nasal provocation and cytokine
levels in nasal secretions, but not peripheral T-cell responses,
in patients with allergic rhinitis

1336 S.G.M.CLOOSTERMAN,T.R.J.SCHERMER,
I. D. BIJL-HOFLAND, S. VAN DER HEIDE,
B.BRUNEKREEF,F.J.J.VAN DEN ELSHOUTS,
WAARDEN & C. P. VAN SCHAYCK
C.L.A.VAN HERWAARDEN & C.P.VAN SCHAYCK
Effects of house dust mite avoidance measures on Der p 1
concentrations and clinical condition of mild adult house dust
mite-allergic asthmatic patients, using no inhaled steroids

1347 M.R.JACOBSON,S.JULIUSSON,O.LOWHAGEN,
B. BALDER, A. B. KAY & S. R. DURHAM
Effect of topical corticosteroids on seasonal increases in
epithelial eosinophils and mast cells in allergic rhinitis: a
comparison of nasal brush and biopsy methods

1356 A. F. HOLM, T.GODTHELP.W.J.FOKKENS,
E. A. W. F. M. SEVERIJNEN, R G. H. MULDER,
T. M. VROOM & E. RIJNTJES
Long-term effects of corticosteroid nasal spray on nasal
inflammatory cells in patients with perennial allergic rhinitis

1367 G.DILORENZO,F.GERVASI,A.DRAGO,
M. ESPOSITO PELLITTERI, A. Dl SALVO,
D. COSENTINO, M. POTESTIO, A. COLOMBO,
G. CANDORE, S. MANSUETO & C. CARUSO
Comparison of the effects of fluticasone propionate, aqueous
nasal spray and levocabastine on inflammatory cells in nasal
lavage and clinical activity during the pollen season in seasonal
rhinitics

1378 C.H.HUGHES.R.C.M. JONES, D.E.WRIGHT&
F. F. DOBBS
A retrospective study of the relationship between childhood
asthma and respiratory infection during gestation

1382 M.D. SHIELDS, V. BROWN, E.G. STEVENSON,
P. S. FITCH, B. C. SCHOCK, G. TURNER, R. TAYLOR &
M. ENNIS
Serum eosinophilic cationic protein and blood eosinophil
counts for the prediction of the presence of airways
inflammation in children with wheezing

1390 P.DEMOLY,F.E.MALY,G.MAUTINO,S.GRAD,
C. GOUGAT, H. SAHLA, P. GODARD & J. BOUSQUET
VEGF levels in asthmatic airways do not correlate with plasma
extravasation

1395 H.-S. PARK, K.-S.JUNG,H.-Y.KIM,D.-H.NAHM&
K.-R. KANG
Neutrophil activation following TDI bronchial challenges to
the airway secretion from subjects with TDI-induced asthma

1402 A. MAY, A. WEBER, H. GALL, R.KAUFMANN&
T. M. ZOLLNER
Means of increasing sensitivity of an in vitro diagnostic test
for aspirin intolerance

1412 S.YOSHIDA,H.MIKAMI,H.NAKAGAWA,
H. HASEGAWA, K. ONUMA, Y. ISHIZAKI, T. SHOJI &
H. AMAYASU
Amalgam allergy associated with exacerbation of aspirin-
intolerant asthma

1415 T.NICHOLS.A.HANSELL&D.STRACHAN
The contribution of 'holiday deaths' to seasonal variations in
astlima mortality in England and Wales

1418 J.M.VEGA,LMONEO,A.ARMENTIA,A.FERNANDEZ,
J. VEGA, R. DE LA FUENTE, P. SANCHEZ &
M. E. SANCHIS
Allergy to the pine processionary caterpillar (Thaumetopoea
pityocampa)

1424 T.ISHIZUKA,Y.OKAYAMA,H.KOBAYASHI&
M. MORI
Interieukin-IO is localized to and released by human lung mast
cells

1433 Book reviews

1434 Forthcoming meetings

1436 Forthcoming articles


 

_________________________________________