Microbes and Infection
VOL. 1 , NO. 1 , 1999
Editorial
S.H.E. Kaufmann.........................................................................................................................................................................................5
DNA vaccines for viral diseases
H.L. Davis and M.J. McCLUSKIE............................................................................................................................................................... 7
The natural resistance-associated macrophage protein
and susceptibility to intracellular pathogens
R.Bellamy................................................................................................................................................................................................ 23
Legal challenges posed by the use of antimicrobials in food animal production
D.P. fidler................................................................................................................................................................................................ 29
Mechanisms underlying genetic differences in T helper subset
differentiation organized by J. Louis and KM. Murphy
Introduction
J. Louis and KM. Murphy....................................................................................................................................................................... 41
Reprogramming transcription during the differentiation of precursor
CD4(+) T cells into effector Thi and Th2 cells
M. Rincon and R.A. Flavell..................................................................................................................................................................... 43
Primed and replicating but uncommitted T helper precursor cells show
kinetics of differentiation and commitment similar to those of naive T helper cells
P. S. Akai and T.R. Mosmann.................................................................................................................................................................. 51
New insight into the mechanisms underlying Th2 cell development
and susceptibility to Leishmania major in BALB/c mice
P. Launois, H. Himmelrich, F. Tacchini-Cottier, G. Milon andJ. Louis................................................................................................. 59
Influence of host and parasite factors on the innate immune
response and Th2 stability following infection with Leishmania major
B. HondffimczandP. Scott....................................................................................................................................................................... 65
Non-MHC-linked genetic polymorphism controls selective development
of Th2 but not inhibition of Th 1 cells by soluble antigen administration
F. GalhiatiandL. Adorini........................................................................................................................................................................ 73
Loci influencing development of Th responses. Identification from in vitro analysis
M.L. Guler, J.D. Gorham, W.F. Dietrich, R. G. Stcen. G. Parvin, D. fenoglio, A. Gmpe, G. Peltz and KM. Murphy...................... 79
Genetic control of T helper subset differentiation in Leishmania major infection of mice
AM. Beebe, D.J. Gua, and R.L. Coffinan................................................................................................................................................ 89
Roles of Nrampi, HLA, and a gene(s) in allelic association with IL-4,
in determining T helper subset differentiation
JM. Blackluell, G.F. Black, C. Sharpies, S.-S. Soo, C.S. Peacock and E.N. Miller................................................................................. 95
Chemokine receptors and other surface molecules preferentially
associated with human Thi or Th2 cells
F. Annanziato, G. Galli, P. Romagnani, L. Gosmi, R. Manetti, E. Maggi and S. Romagnaai.............................................................. 103
Instructions for Authors................................................................................................................................................................. 107
Addresses of Editorial Board Members .................................................................................................................................. 109
_______________________________________
Microbes and Infection
VOL. 1, NO. 2, 1999
Introduction of protein or DNA delivered via recombinant
Salmonella typhimurium into the major histocompatibility complex class I presentation
pathway of macrophages
A. Catic, G. Dietrich, 1. Gentschev, W. Goebel^ S.H.E. Kaufmann and ]. Hess..................................................................................... 113
Novel variant of the CCR5 gene in a Vietnamese population
M. Magierowska, V. Lepage, T.X. Lien, N.T. Homlg Lan, AI. Gaillotcl,
H. issafras,J.-M. Reynes, H. J.A. Flenry, N.H. Chi, ].-Y. FoMon,
P.Debre, l.Theodorou andF. Barre-Sinonssi ........................................................................................................................................... 123
Antimicrobial properties of allicin from garlic
S. Ankriand D. Mirelman....................................................................................................................................................................... 125
Molecular pathogenesis of Bacillus anthracis infection
S.F. Little and B.E. lvins.......................................................................................................................................................................... 131
Pathogenesis of Cryptosporidium parvum infection
F. Laurent, D. McCole, L. Eckmann and M.F. Kagnoff........................................................................................................................... 141
The flagellated parasite Trichomonas vaginalis:
new insights into cytopathogenicity mechanisms
P.L. Fiori, P. Rappelli and M.F. Addis..................................................................................................................................................... 149
Current studies on the pathogenesis of melioidosis
D.E. Woods, D. DeShazer, R.A. Moore, P.]. Brett,
M.N. Burtnick, S.L. Reckseidler, M.D. Senkiw....................................................................................................................................... 157
Instructions for Authors................................................................................................................................................................. .............. 163
Addresses of Editorial Board Members ..................................................................................................................................................... 165
_______________________________________
Microbes and Infection
VOL. 1 , NO. 3 , 1999
A Journal on Infectious Agents and Host Defenses
Editorial............................................................................ 169
" (gamma b )T lymphocytes, a link between immunity and homeostasis?"
organized by M. Bonneville................................................. 171
Introduction
M. BonnevilleandJ.-J. Fournie .............................................. 173
Recognition of nonpeptide prenyl pyrophosphate antigens by human y8 T cells
C.T. Morita H.K. Lee, D.S. Leslie, Y. Tanaka, J.F. Bukowski and E. Märker-Hermann ............. ............................................... 175
y8 T cells and Mycobacterium tuberculosis
W. H. Boom....... ...................................................................... 187
Activation of (gamma b )T cells by mycobacterial antigens in rheumatoid arthritis
J.Holoshitz................................................................................. 197
TCR (gamma b ) cells and viruses
R. SciammasandJ.A. Bluestone................................ ....................... 203
Human (gamma b) T cells and viruses
J. Dechanet, P. Merville, V. Pitard, X. Lafarge and J.-F. Moreau........... .............. 215
NKR-mediated control of yS T-cell immunity to viruses
M.-L. Gougeon, S. Boullier, V. Colizzi and R Poccia............. ..... .............................. 219
Role of (gamma b ) T cells in tumor immunity and their control by NK receptors
A. Moris, S. Rothenfilsser, E. Meuer, R. Hangretinger and P. Fisch...................................................................................................... 227
The role of intraepithelial y8 T cells: a gut-feeling
R. Boismenu, Y. Chen and W.L. Havran............................................................................ 235
Immunoregulatory functions of mucosal(gamma b ) T cells
M. YamamotoandH. Kiyono................................................................................................................................................................... 241
Activation and control of self-reactive ( gamma b ) T cells
F. Halary, ].-]. Foumie and M. Bonneville.............................................................................................................................................. 247
Effector functions and control of human yo T-cell activation
D.Kabelitz. ................... ................................................................................................... 255
Control of ( gamma b )T cells by NK receptors
G. DC Libero. ................................................................................................................... 263
Instructions for Authors...................................................................................................... 269
_______________________________________
Microbes and Infection
VOL. 1 , NO. 4 , 1999
Differential antibody isotype expression to the major Paracoccidioides brasiliensis antigen in juvenile
and adult form paracoccidioidomycosis
H. Baida, P.J.C. Biselli, M. Juvenale, GM.B. Del Negro, M.J.S. Mendes-Giannini, A.J.S. Duarte and G. Benard.................................... 273
Human cytomegalovirus genome sequences in lymph nodes
Y.S. Boriskin, P. Moore, A.]. Murday, J.C. Booth and P.D. Butcher. ...................................................................................................... 279
Microbial interactions in the vaginal ecosystem, with emphasis on the pathogenesis of bacterial vaginosis
V. Pybus and A.B. Onderdonk................................................................................................................................................................. 285
Pathogenicity of Cryptococcus neoformans: virulence factors and immunological mechanisms
M.L. Rodrigues, C.S. Alviano and L.R. Travassos.................................................................................................................................. 293
An evolutionary view of the interactions between anopheline mosquitoes and malaria parasites
J.C. Koella..................................................................................................................................................................................................303
Human retroviral sequences associated with extracellular particles in autoimmune diseases:
epiphenomenon or possible role in aetiopathogenesis?
H. Perron and J.M. Seigneurin................................................................................................................................................................ 309
Yersinia enterocolitica: overview and epidemiologic correlates
EJ.Bottone............................................................................................... ..................................................................................................... 323
The effect of viruses on the ability to present antigens via the major histocompatibility complex
V. B. Peters and K,E. Serber..................................................................................................................................................................... 335
Adresses of Editorial Board Members....................................................................................................................................................... 347
Instructions for Authors................................................................................................................................................................. .............. 349
_______________________________________
Microbes and
Infection
A Journal on Infectious Agents and Host Defenses
Vol. 1-No. 5- 1999
Contents
Meeting report on vaccinology
D. Laouini, N. Pardigon and P. Konrttsky............................................................................................................................................... 361
Clinical and biological aspects of infection caused by Ehrlichia chaffeensis
^^^zsfl.................................................................................................................................................................................................. 367
Antibiotics and Clostridium difficile
}. Freeman and M.H. Wilcox.................................................................................................................................................................... 377
Molecular basis of defence against oxidative stress in Entamoeba histolytica and Giardia lamblia
385
Magic bullets need accurate guns - syphilis eradication, elimination, and control
G.P.Garnett and R.C.Brunham.............................................................................................................................................................. 395
Instructions for Authors................................................................................................................................................... .......... 405
________________________________________
Microbes and Infection
Vol:1, No: 6, may 1999
Characterization of low-density lipoprotein uptake by murine macrophages exposed to Chlamydia
pneumoniae
M.V. Kalayoght, G.S. Miranpuri, D.T. Golenbock and G.I. Byrne......................................................................................................... 409
Expression and role of heat-shock protein 65 (HSP65) in macrophages during Trypanosoma cnizi
infection: involvement of HSP65 in prevention of apoptosis of macrophages
T. Sakai, H. Hisaeda, H. ishikawa, Y. Maekawa, M. Zhang, Y. Nakoo, T. Takeuchi, K. Matsumoto, R.A. Good and K. Himeno........ 419
The potential use of heat-shock proteins to vaccinate against mycobacterial infections
C.L.Silva.................................................................................................................................................................................................. 429
The pathogenesis of Acanthamoeba keratitis
]. Y. Niederkorn. H. Alizadeh. H. Leher and J.P. McCulley..................................................................................................................... 437
Probing the microenvironment of intracellular bacterial pathogens
O.S.Harb and YAhlKwfllfc................................................................................................................................................................... 445
The epidemiology of Neisseria gonorrhoeae in Europe
Y.T.H.P.van Duynhoven ........................................................................................................................................................................ 455
Evolutionary genetics of Trypanosoma and Leishmania
M.Tibayrencand FJ. Ayala .....„...............................................................................................................................................——.....—• 465
Addresses of Editorial Board Members 473
Instructions for Authors 475
Submission form 477
________________________________________
Microbes and Infection
VOL: 1, NO: 7, JUNE 1999
'Immunoregulationofschistosomiasis'
organized by M. Capron and A. Capron ................................................................................................................................................ 481
Introduction
A. Capron and M. Capron....................................................................................................................................................................... 483
Regulation of the immune response in experimental and human schistosomiasis: the limits of an attractive paradigm
A. Capron, D. Dombrowicz and M. Capron............................................................................................................................................ 485
Immunoregulation within the granulomas of marine schistosomiasis mansoni
J.V. Weinstock, D. Elliott, A. Metwali, A. Blum, ]. Li, K. Qadir and M. Sandor...................................................................................... 491
The schistosome granuloma : an immunoregulatory organelle
C.A.RumbleyandSM.Phillips............................................................................................................................................................ ..........499
The development of granulomas in schistosomiasis: genetic backgrounds, regulatory pathways,
and specific egg antigen responses that influence the magnitude of disease
M.J.Stadecker........................................................................................................................................................................................... 505
T helper cell populations, cytokine dynamics, and pathology of the schistosome egg granuloma
D.L.Boros................................................................................................................................................................................................. 511
Infection-stimulated or perinatally initiated idiotypic interactions can direct differential morbidity and
mortality in schistosomiasis
D. G. Colley, M. A. Montesano, G. L. Freeman, W. E. Secor................................................................................................................. 517
Immune deviation as a strategy for schistosomiasis vaccines designed
to prevent infection and egg-induced immunopathology
TAW/nfi.................................................................................................................................................................................................... 525
Strategies for a schistosome vaccine: can we manipulate the immune response effectively ?
R.A. WilsonandP.S.Coulson..................................................................................................................................................................... 535
Role of interleukin-7 in the relation between Schistosoma mansoni and its definitive vertebrate host
I.Wolowczuk, 0. Roye, S. Nutten, M. Delacre, F. Trottein and C. Auriault.............................................................................................. 545
Immunology of hepatosplenic schistosomiasis mansoni : a human perspective
D.W.Dunne and E.]. Pearce.................................................................................................................................................................... 553
Infection and disease in human schistosomiasis mansoni are under distinct major gene control
A.J. Dessein, S. Marquet, S. Henri, N. Eldin, M.A. El Wali, D. Hillaire, V. Rodrigues, A. Praia, Q.M. Ali, B. Gharib,
M. de Reggi, MM.A.Magzoub, O.K. Saeed, A.A. Abdelhameedand L.Abe}............................................................................................ 561
Commentary on the Forum..................................................................................................................................................................... 569
Addresses of Editorial Board Members.................................................... ............................................................................................. 575
Instructions for Authors............................................................................................................................................................................ 577
_______________________________________
MICROBES & INFECTION
VOL. 1, NO. 8, JULY 1999
Defective priming of the phagocyte oxidative burst in a child with recurrent intracellular infections
C. Elbim, P. Rajagopalan-Levasseur, S. ChoUet-Martin,J.-L. Gaillard, M. Fay , /. Hakim,
A.Fischer, J.-L. Casanova and M.-A. Gougerot-Pocidalo............................................................................................................. 581
Leishmania major proteophosphoglycan is expressed by amastigotes and has an immunomodulatory
effect on macrophage function
A Piani, T. llg, A.G. Elefanty, /. Curtis and E. Handman.......................................................................................................... 589
Antiapoptotic activity of herpes simplex virus type 2: the role of US3 protein kinase gene
S. Hata, A.H. Koyama, H.Shiota, A. Adachi, F.Goshima and Y. Nishiyatna............................................................................ 601
Myristic acid analogs are inhibitors of Junin virus replication
SM. Cordo, N.A. Candurra and E.B. Damonte.............................................................................................................................. 609
Genomic clues for defining bacterial pathogenicity
N.R. Salama and S. Falkow.................................................................................................................................................................. 615
Perturbation and exploitation of host cell cytoskeleton by periodontal pathogens
R.P.Ellen................................................................................................................................................................................................ 621
Role of complement in host defense against bacterial infection
C. Mold................................................................................................................................................................................................... 633
The effects of antibiotic usage in food animals on the development of antimicrobial resistance
of importance for humans in Campylobacter and Escherichia coli
FM. Aarestrup and H.C. Wegener.................................................................................................................................................... 639
Infectious web'..................................................................................................................................................................................... 645
Addresses of Editorial Board Members........................................................................................................................................... 647
Instructions for Authors...................................................................................................................................................................... 649
_______________________________________
_______________________________________
Microbes and Infection
VoL . 1 , No. 9, 1999
Toxoplasmagondii motility and host cell invasiveness are drastically impaired by jasplakinolide, a cyclic peptide
stabilizing F-actin
O.Poupel and I.Tardieux 653
Search for an antibody profile of Rhodococcus equi infection in AIDS patients despite the diversity of isolates
and patient immune dysfunction
A. Cterino-de-Araujo, E. de los Smltos-Fortnna, M. C Zamlotm-Mdeiro, C M. Mastroianni,M- Lichtner, F. Mengoni
and V. Vullo 663
Cell-dependent replication potentials of HIV-1 gag imitants
A. Adachi, M. Tamakl, R. Shimano,R. lnubushi, T. Naito, K. Yoshida, Y. Oshima M. Kawamura and A. Hajime Koyama 671
Isolation and characterization of a rnonoclonal antibody that inhibits HIV-I infection
D.-X.Fu,A,Jinno,N, Shimmy Y,Harngiichiand H. Hoshino 677
Mucosal immunization with DNA vaccines
M. J. McChiskieand H, L Davis 685
T lymphocyte-dependent effector mechanisms of immunity to Toxophsma gondti
E. Y. Denkers 699
Roles of lipoarabinomannan in the pathogenesis of tuberculosis
G- R. Strohmeierand M. J. Fenton 709
Host cytokine response and resistance to Salmonella infection
A.-C. Lllimanach and E Lantier 719
Phagocytosis of microorganisms by means of overshooting pseudopods: where do we stand?
M.G.Rittig,B. Wilski and A. Krause 727
Infectious web 737
Instructions for Authors 739
Addresses of Editorial Board Members 741
Microbes and Infection
Vol. 1, No. 10, 1999
Integrin-associated protein (IAP)-deficient mice are less susceptible to
developing Staphylococcus aureus-induced arthritis
M. Verdrengh, F.P. Lindberg, C. Ryden and A. Tarkowski 745
Cytolytic T-cell responses to human dentritic cells and macrophages infected with
Mycobacterium bovis BCG and recombinant BCG secreting listeriolysin
P.Conradt.J.HessandS.H.E. Kaufmann 753
Experimental conditions that increase the production of HIV-1 by
monocyte-derived macrophages: use of collagen matrix
C.M. Godard andJ.-C. 765
Increase in CD(3+) CD(4-) T lymphocytes in patients with AIDS and
disseminated Mycobacterium avium"intracethtlare complex infection: a prospective study
R Bonnet, L Dequae-Merchadou, J,"L. Taupin, S. Sue, M. Dapon, J.-M. Ragnaud, D. Lacoste,
J. Texier-Maugein, F, Romagne, R Dabis, J.-L. Pellegrin, J.-F. Morenu and the GECSA 771
A review of oral vaccination with transgenic vegetables
C.O.Tacket and HS, Mason 777
Complement-resistance mechanisms of bacteria
R. Rauternaa and S. Men 785
Antimicrobial resistance in Staphylococcus aureus
T.L. Smith and 795
Host-parasite interaction in bovine infection with Tritrichomonas foetus
R.S.J. Felleisen 807
Molecular epidemiology, pathogenesis, and genetics of the dimorphic fungus Histoplasma capsulfitum
D.M.Retallackondf.P. Woods 817
'Infectious web 827
Instructions for Authors 829
Microbes and Infection
Vol. 1 , No. 11, 1999
'Regulation of major histocompatibility complex class II gene expression'
organized by W. Reith 833
Introduction
W. Reith 835
A tribute to Donald Pious (1930-1998)
M- Feihus 837
The molecular basis of MHC class II deficiency and transcriptional control of MIIC class II gene expression
W. Reith. A. Muhlethaler-Mottet. K. Masternak J. Villard and B, Mach 839
A common set of factors control the expression of the MHC class II, invariant chain, and HLA-DM genes
JM. Boss 847
Class II MHC genes: a model gene regulatory system with great biologic consequences
J.P.Y. Ting and X.-S. Zhu 855
855
The class II transactivator CIITA is a transcriptional integrator
J.D. Fontes, S. Kanaza-lua, N. Nekrep and BM. Prterlin 863
MHC class II gene regulation: some historical considerations on a still ontogenetic and phylogenetic puzzle
R.S. Accolh, G. Tosi, S. Sarhris and A. DC Lerma Barbaro 871
Class II transactivator: is it a master switch for MHC class II gene expression?
C.-H. Chang, S. Roys and T. Gourley 879
The common regulatory pathway of MHC class I and class II transactivadon
P.J. van den Elsen and S.J.P. Gobin 887
Regulation of MHC class II expression in the central nervous system
J.F. Collawn and E.N. Benveniste 893
MHC class II regulation in vivo in the mouse kidney
TX Sims and P.F. Halloran 903
HLA class II expression in human tumor lines
G. Blanck 913
Allelic variation in transcription modulates MHC class II expression and function
J.S. Beaty, T.L Sukiennicki and G.T. Nepom 919
Differential expression of MHC class II isotype chains
C Alcaide-Loridan, A.-M. Lennon, M.-R. Bono, R. Barbouche, K. Dellagi mid M. Feliotts 929
Mechanism of I-A(beta) gene expression
J. Lloberas, C Soler and A. Celada 935
Regulation of HLA class II gene expression: the case for posttranscriptional control levels
C Del Pozzo, M. Cndto and J. Guardlola 943
Commentary on the Forum 949
Addresses of Editorial Board Members 955
Instructions for Authors 957
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MICROBES & INFECTION
VOL. 1, NO. 12, 1999
Role of ICAM-I (CD54) in the development of inurine cerebral malaria
N. Favre, C. Da Laperousaz, B. Ryffel, N.A. Weiss, B.A. lmhof, W. Rudin, R. Lucas and P.F. Piguet. ............. 961
Prion protein and neuronal differentiation: quantitative analysis of prap gene expression in a munne
inducible neuroectoderrnal progenitor
S. Mouillet-Richard, I. Lanrendeau, M. Vidalul, 0. Kcllci'manii and J.-L. LaplanGfic ............................ 969
Accumulation of MAC387^ macrophages in paracortical areas of lymph nodes in rhesus monkeys
acutely infected with simian immunodeficiency virus
I. Otam. K. Mori, T. Satn, K. Terao, K. Doi. H. Akan mid Y. Yoshikawa. ...................................... 977
Establishment of a persistent mutant of canine distemper virus
K. lwatsllki, Y. lkeda, K. Ohashi, K. Nakninum ami C. Kai.................................................. 987
SecA: the ubiquitous component of preprotein translocase in prokaryotes
M.G. Schmidt and K.B. Kiser .......................................................................... 993
Pathogenicity of microbes associated with cystic fibrosis
MI. Hutchisn and J.R. W. Govan ...................................................................... 1005
Epidemiology and immunopathology of bancroftian filariasis
A.B. de Almeida and D.O. Freedman .................................................................... 1015
Pathophysiology of Campylobacter jejuni infections of humans
TM. Wassenaar and M.J. Blaser........................................................................ 1023
Laboratory methods of diagnosis of syphilis for the beginning of the third millennium
K. Wicher, H. W. Horolvitz and V. Wicher ................................................................ 1035
Learning from cholera: medical and social responses to the first great Paris epidemic in 1832
C.J. Kudlick.......................................................................................... 1051
Facing the global challenges posed by biological weapons
D.P. Fidler........................................................................................... 1059
Addresses of Editorial Board Members .............................................................. 1067
Instructions for Authors ............................................................................ 1069
_______________________________________
Microbes and Infection
VoL. 1, No. 13, 1999
Comparison of an antiviral activity of recombinant consensus interferon with recombinant
interferon-(alfa)-2b
AM. Koyama, T. Arakaiva and A. Adachi 1073
Early events in dendritic cell maturation induced by LPS
E Granucci, E, Ferrero, M. Foti, D. Aggujaro, K. Vettoretto and P. Ricciardi-Castagnoti 1079
Diagnostic value of dengue virus-specific IgA and lgM serum antibody detection
J. Groen,J. Vehing, C. Copra, E. Balentien, V. DeuM, V, Vorndam and AD.M,E. Osterhaas 1085
Correlation of serum hepatitis C virus RNA titre with aminotransferases and liver histopathological
findings in HCV-seropositive cases with end-stage chronic liver disease
S. Agha, M. Al-Gendy, A. El'Fiky and W. El-Emshaty 1091
Evaluation of lgG, lgM, and igA antibodies to Mycoplasma penefrans detected by ELISA
and immunoblot in HIV-l-infected and STD patients, in Sao Paulo, Brazil
CMM. de Cordova, K, Takei, C Rosenthat, M.A.R.B. Miranda, A.J. Vaz and R.A.R da Cunha 1095
Bacterial phospholipases and pathogenesis
DM. Schmiet and V. L. Miller 1103
HIV-infected long-term nonprogressors: epidemiology, mechanisms of delayed progression,
and clinical and research implications
S. Buchbinder and E. ViHinghoff 1113
Pathogenesis otMycobacterium avium subspecies paratuberculosis infections in ruminants:
still more questions than answers
P. Valentin-Weigand and R. Goethe 1121
Enterotoxins in Aeromomis-associated gastroenteritis
A.K. Chopra and CIV Houston 1129
The role of the epidermal growth factor receptor in microbial infections of the gastrointestinal tract
A. Buret, D. Grant Gall, ME. Olson and J.A. tiardin. 1139
'Infectious web' 1145
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