RISK ANALYSIS


Volume 19, Number 1, February 1999


Opening Editorial 1
Elizabeth L. Anderson

LETTERS TO THE EDITOR
Response to 'Eyes Closed: Simple, Intuitive, Statistically Sound, and Efficient Methods for Estiriiating
Parameters of Clonal Growth Cancer Models' 3
Rory B. Conolly and David A. Kramer


Response to Comments on 'An Approach for Modeling Noncancer Dose Responses with an Emphasis
on Uncertainty' and 'A Probabilistic Framework for the Reference Dose (Probabilistic RfD)' 7
PaulS. Price, Russ Keenan, Jeff Swartout, and Michael Donf^o/l

ARTICLES

An Alternative Exact Solution of the Two-Stage Clonal Growth Model of Cancer 9
Rudolf T. Hoogenveen, Harvey J. Clewell, Melvin E. Andersen, and Wont Sloh


A Comparison of Regulatory Implications of Traditional and Exact Two-Stage Dose-Response Models 15
Weihsueh A. Chin, David M. llassen^ahl, and Daniel M. Kainmen


Context in the Risk Assessment of Digital Systems 23
Chris Garrett and George Ap.ostolakis


Mixed Levels of Uncertainty in Complex Policy Models 33
Elizabeth A. Gasman, M. Granger Morgan, and Hadi Dowlatabadi\

SPECIAL COLLECTION: Workshop Proceedings for 'When and How Can You Specify a Probability
Distribution When You Don't Know Much?' Part II


Workshop Overview 43
Yacov Y, Haimes and James H. Lambert


Foundations 47
Elizabeth L. Anderson, Dale Hattis, Nicholas Matalas, Vicki Bier, Stan Kaplan, David Bnrmaster,
Steve Conrad, and Scott Person

Decision-Making with Heterogenesis Sources of Information 69
Donald Richards and William D. Rower


A Survey of Approaches for Assessing and Managing the Risk of Extremes 83
Vicki M. Bier, Yacov Y, Haimes, James H. Lambert, Nicholas C. Matalas, and Rae Zimmerman


What Should be the Implications of Uncertainty, Variability, and Inherent 'Biuscs'/'Conservatism' for Risk
Management Decision-Making? 95
Dale Hattis and Elizabeth L. Anderson


Methods for Characterizing Variability and Uncertainty: Comparison of Bootstrap Simulation and
Likelihood-Based Approaches 109
h. Christopher Frey and David F. Burmaster


Beyond the Domain of Direct Observation: How lo Specify a Probability Distribution that Represents the
'State of Knowledge' About Uncertain Inputs 131
F. Owen Hoffman and Stan Kaplan


The Expected Value of Information and the Probability of Surprise 135
James K. Hammit and Alexander I. Shlyakhter


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Risk Analysis

Volume 19, Number. 2, April 1999

CONTENTS

EDITORIAL

The Role of the Society for Risk Analysis in the Emerging Threats to Critical Infrastructures 153
Yacov Y. H dimes

ORIGINAL ARTICLES


Geographical Dimensions and Correlates of Trust 159
Michael R. Greenberg and Bryan Williams


Who Lives Near Coke Plants and Oil Refineries? An Exploration of the Environmental Inequity Hypothesis 171
John D. Graham, Nancy Dean Beaulieu, Dana Sussman, March Sadowiu, and Yi-Ching Li


Combining Probability Distributions from Experts in Risk Analysis 187
Robert T. Clemen and Rober L. Winkler


Public Support for Earthquake Risk Mitigation in Portland, Oregon 205
James Flynn, Paul Slovic, C. K. Mertz, and Cathie Carlisle


Fishing in Urban New Jersey: Ethnicity Affects Information Sources, Perception, and Compliance 217
Joanna Burger, Kerry Kirk Pflugh, Lynette Lurig, Leigh Ann Van Hagen, and Stanley Von Hagen


Fundamentals of Health Risk Assessment. Use, Derivation, Validity and Limitations of Safety Indices 231
Resha M. Put^rath and James D. Wilson


Reliability Analysis for Hazardous Waste Treatment Processes 249
Robert D. Waters and Frank L. Parker
Hormesis: A Highly Generalizable and Reproducible Phenomenon with Important Implications for


Risk Assessment 261
Edward J. Calabrese, Linda A. Baldwin, and Charles D. Holland


Adverse Health Experiences, Environmental Attitudes, and Pesticide Usage Behavior of Farm Operators 283
Erik Lichtenberg and Rae Zimmerman


Estimating Noncancer Uncertainty Factors: Are Ratios of NOAELs Informative? 295
Kevin P. Brand, Lorenz Rhomberg, and John S. Evans


Cancer Risk Estimation of Genotoxic Chemicals Based on Target Dose and a Multiplicative Model 309
Fredrik N. Granafh, Carlos E. Vaca, Lars G. Ehrenberg, and Margareta A. Tomqvist

Announcement 321


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Risk Analysis
Volume 19, Number 4, August 1999

CONTENTS

ARTICLES
Exposure to Persistent Organochlorines in Canadian Breast Milk: A Probabilistic Assessment 527
Sara M. Hoover

Evaluation of the Uncertainty in an Oral Reference Dose for Methyirnercury Due to Interindividual Variability

in Pharmacokinetics 547
Harvey J. Clewell, Jeffery M. Gearhart, P. Robinan Gentry, Tammie R. Covington, Cynthia B. VanLandingharn,
Kenny S. Crump, and Annette M. Ship?

Evaluation of Atmospheric Transport Models for Use in Phase II of the Historical Public Exposures Studies at the

Rocky Flats Plant 559
Arthur S. Rood, George G. Killongh, and John E. Till

Estimating Risk Assessment Exposure Point Concentrations when the Data Are Not Normal or Lognormal 577
Terry W. Schul?. and Susan Griffin

Uncertainty in Comparative Risk Analysis for Threatened Australian Plant Species 585
Mark A. Burgman, David A. Keith, and Terry V. Walshe

Quantitative Assessment of the Risk of Lung Cancer Associated with Occupational Exposure to Refractory

Ceramic Fibers 599
Suresh H. Moolgavkar, E. Georg Luebeck, Jay Turim, and Linda Hanna

Statistical Evaluation of Population Data for Calculation of Radioactive Material Transport Accident Risks 613
G. Scott Mills and K. Sieglinde Neuhauser

The Power of Perception: Health Risk Attributed to Air Pollution in an Urban Industrial Neighbourhood 621
Susan J. Elliott, Donald C. Cole, Paul Krueger, Nancy Voorberg, and Sarah Wakefield

Economic Impact of Accelerated Cleanup on Regions Surrounding the U.S. DOE'S Major Nuclear Weapons Sites 635
Michael Greenberg, Laura Solifarc, Michael Frisch, and Karen Lowrie

"How Exposed Is Exposed Enough?" Lay Inferences About Chemical Exposure 649
Donald G. MacGregor, Paul Slavic, and Torbjorn Malmfors

A Model of Consumers' Risk Perceptions Toward Recombinant Bovine Growth Hormone (rbGH): The Impact

of Risk Characteristics 661
Deana Grobe, f^obin Douthilt, and Lydia Zepeda

Simultaneous Analysis of Individual and Aggregate Responses in Psychometric Data Using Multilevel Modeling 675
lan 11. Longford, Claire Morris, Anne-Lise Me Donald, Harvey Goldstein, Jon Rasbash, and Tim O'Riordan
1997 Annual Meeting of the Society for
Risk Analysis: Invited Nugget Papers

Editorial on the Nugget Papers 685
Yacov Y. Haimes

Trust, Emotion, Sex, Politics, and Science: Surveying the Risk-Assessment BattleFleld 689
Paul Sl'ovic

Challenges to the Acceptance of Probabilistic Risk Analysis 703
Vicki M. Bier

Human Interindividual Variability in Parameters Related to Health Risks 711
Dale Hattis, Prerna Banati, Rob Goble, and David E. Burmaster

The Complementary Roles of Mitigation and Insurance in Managing Catastrophic Risks 727
Paul R. Kleindorfer and Howard Kunreuther

Bayesian Forecasting via Deterministic Model 739
Roman Krzys^tofowicz

A Perspective on Nuclear Waste 751
D. Warner North