SYNLETT
SPECIAL ISSUE

835
from Corrin Chemistry to Asymmetric Catalysis -
A Personal Account
A. Pfaltz

843
New Gem- and Vic-Disubstituent Effects on
Cyclizations
M. E. Jung

847
The Development of Chiral, Nonracemic Dioxiranes
for the Catalytic, Enantioselective Epoxidation of
Alkenes
S. E. Denmark, Z. Wu

860 Construction of the 6-Azabicyclo[3.2.1]octane Ring
System via Higher-Order Cycloaddition; Formal
Total Synthesis of (±)-Peduncularine
J. H. Rigby, J. H. Meyer

863
A Versatile New Synthesis of 3-Aryl-3H-benzofuran-
2-ones
P. Nesvadba, L. Bugnon, P. Dubs, S. Evans
865An Alternative Synthesis of a Potent GPIIb/llla
Receptor Antagonist
J. F. Hayes

867 Iridium Ferrocenyi Diphosphine Catalyzed Enantio-
selective Reductive Alkylation of a Hindered Aniline
H.-ü. Blaser, H.-P. Buser, H.-P. Jalett, B. Pugin, F. Spindier

869 Introduction of5-Formyl-2'-deoxyuridine into a KB
Site: Critical Discrimination of a Base Structure in
the Major Groove by NFieB p50 Homodimer
A. Kittaka, C. Horii, T. Kuze, T. Asakura, K. Ito, K. T. Nakamura,
T. Miyasaka, J.-i. Inoue

873 A Second-Generation Cycloaddition Route to 5-
Substituted 3-Acyltetramic Acids
R. C. F. Jones, C. E. Dawson, M. J. O'Mahony

877
Conversion of Ascomycin into its Furano-lsomers
K. Baumann, B. Oberhauser, G Stmadt, H. Knapp, G Schulz,
M. A. Grassberger

881
The Sakurai Reaction of 4-Acetoxycyclopentenone -
Synthesis of trans-3-Allyl-4-vinylcyclopentanone
V. Heibling, M. K. Eberle, R. Keese

885 Syntheses of the D-Aldopentoses from Non-carbo-
hydrate Sources
M. G Banwell, C. De Savi, D. C. R. Hockless, S. Pallich,
K. G Watson

889 4-Diazocyclohexa-2,5-dienone Derivatives as
Photoaffinity Labels for Proteins: Scope and
Limitations
C. Colas, T. Grutter, M. Goeldner

893 Site-Selective Epimerization of a Fungal Cycio-
depsipeptide via a 5-Aminooxazole Intermediate
B. Oberhauser, K. Baumann, B. Grohmann, H. Spemer

897 GMP Synthetase: Synthesis and Biological Evalua
tion of a Stable Analog of the Proposed AMP-XMP
Reaction Intermediate
E. J. Salaski, H. Maag

901 Total Synthesis of (±)-Phytochromobilin Starting
from Two Pyrrole Derivatives
T. Kakiuchi, H. Kinoshita, K. Inomata

905 Z-DNA Formation by 2'-C-Ethynyl-modified
Oligonucleotides
R. Buff, J. Hunziker

909 Trials for the Synthesis of (R)-4-Mercapto-pyrroli-
din-2-one ((R)-MPD)
S. Kobayashi, K. Kobayashi, K. Hirai

913 Bicyclo[3.2.1]amide-DNA; Synthesis and Base-
Pairing Properties
A. Egger, C. J. Leumann

917 Interactions of Amino Acid Side Chains with
Nucleobases in Alanyl-PNA
U. Diederichsen, D. Weicherding

921 6-Amino[14]aneS4: A New Amine-Functionalised
Crown Chalcogenide
L. R. Sutton, A. J. Blake, P. A. Cooke, R. 0. Gould, S. Parsons,
M. Schrôder

925 The Novel Sequence Diels-Alder Reaction/lreland-
Claisen Rearrangement Applied to Acyclic Dieno-
philes: New Insights into the Selectivity of the
Ireland-Claisen Rearrangement
J. Velker, J.-P. Roblin, A. Neels, A. Tesouro, H. Stoeckli-Evans,
F.-G Klaemer, J.-S. Gehrke, R. Neier

930 Automated RNA-Synthesis with Photocleavable
Sugar and Nucleobase Protecting Groups
A. Stutz, S. Pitsch
935 Configurational and Conformational Control on
Formation and Oligomerization of 2-C Mono-
Arylated Pseudo-Proline Dipeptide Building Units
by Aromatic Stacking Interactions
M. Keller, M. Mutter, C. Lehmann

940 Pyranosyl-RNA Supramolecules Containing
Non-Hydrogen Bonding Base-Pairs
c. hamon, T. Brandstetter, N. Windhab

945 A Novel Procédure for the Formation of Isatins
via Carbonylation of Lithiated N-Aryl-N,N
dimethylureas
K. Smith, G A. EI-Hiti, A. C. Hawes

948 Synthesis of Racemic Ribose from D-Glucose
C. Miculka

951 Construction of Eight-Membered Carbocycles
by Palladium-Catalyzed [4+4] Cycloaddition of
Vinylallenes
M. Murakami, K. Itami, Y. lto

954 A Bromoarene Based Approach to Phenylalanine
Analogues Hie and Nic
S. E. Gibson (née Thomas), J. 0. Jones, R. McCague, M. J. Tozer,
N. J. Whitcombe
975 A Synthesis of Taxanes by Lactam-sulfoxide Ring
Contraction and Intramolecular Pinacol Coupling
K. Takatori, Y. Takeuchi, Y. Shinohara, K. Yamaguchi,
M. Nakamura, T. Hirosawa, T. Shimizu, M. Saito, S. Aizawa,
0. Sugiyama, Y. Ohtsuka, M. Kajiwara

978 Synthesis of an RNA-Peptide Conjugate by
Orthogonal Ligation

M. McPherson, M. C. Wright, R A. Lohse

981 Characterization of Caged Cholinergic Ligands;
Sulfonated Calix[4]arene Inclusion Complexes
A. Specht, M. Goeldner, J. Wirz, L. Peng

984 Addition of 2-Lithiothiazoles to ROPHy/SOPHy
Aldoximes: Asymmetric Synthesis of l-(2-Thia-
zolyl)ethylamines
C. J. Moody, J. C. A. Hunt

987 An Efficient Formal Total Synthesis of (±)-Stypol-
dione via Photochemically Triggered Biomimetic
Cyclizations of Terpenoid Polyalkenes
X. Xing, M. Demuth

991 The "Triamino-analogue''^ of Methyl Cholate;
A Practical, Large-Scale Synthesis
A. P. Davis, M. N. Perez-Payan
957 A Highly Efficient Preparation of Methacrylate
Esters using Novel Solid Phase Titanium-based
Transesterification Catalysts
N. Lewis, C. Ribas, A. Wells

960 Carba-Methylephedrine and Carbâ-pseudo-
Methylephedrine as Tools for Probing the Role of
the Nitrogen Atom of Chiral Amino Alcohols in
Asymmetric Synthesis
D. Cahard, L. Perron, J.-C. Plaquevent

963 Coupling Reagent Dependent Regioselectivity in the
Synthesis of Lysine Dipeptides
S. Shatzmiller, P. N. Confalone, A. Abiri

966 Synthesis of a Chiral Receptor Molecule with
Converging Amidinium and Hydroxy Groups
T. Schuster, M. W. Gobel

969 Calixporphyrin - a New Type of Porphyrinoid Con
tainer Molecule
J. Schlogi, B. Krautler

972 Enantioselective Synthesis of Alkyl-substituted
Eight-membered Lactones by Claisen Rearrange
ment
J. R. Harrison, A. B. Holmes, 1. Collins
994 Synthesis and Conformation of a Novel Dipeptide
Derived from a y-Amino Acid with Norbornane
Skeleton
J. Duwenhorst, R-P. Montforts

997 Synthesis of 3-Alkoxy- and 3-Alkylamino-2-alkyl-3-
arylisoindolinones
M. S. Kitching, W. Clegg, M. R. J. Elsegood, R. J. Griffin,
B. T. Golding

1000 Synthesis of Two Novel Cyclic Biphenyl Ether
Analogs of an Inhibitor of HCV NS3 Protease
A. Marchetti, J. M. Ontoria, V. G Matassa

1003 The Copper(l) Catalysed [2+2] Intramolecular
Photoannulation of Carbohydrate Derivatives
D. J. Holt, W. D. Barker, P. R. Jenkins, S. Ghosh, D. R. Russell,
J. Faweett

1006 Stereoselective Entry to the Bicycle [4.3.0] Skeleton
of Opiopanes Using a Transannular Cyclization
Strategy I
G Delgado, S. Guzman

_______________________________________

SYNLETT
NO:3, MARCH 1999
269 Utilization of the Stannyl Anionic Species Generated
from McySiSnBua and X~ in Organic Synthesis
M. Mori,* N. Isono, H. Wakamatsu

281 Ruthenium-Catalyzed Coupling Reactions of Alk-
ynes and Alkenes
C. S. Yi,* N. Liu

288 A Direct Conversion of Alkenes to Isocyanides
Y. Kitano,* K. Chiba, M. Tada

291 Novel Tocopherol Compounds XL Synthesis,
Bromination and Oxidation Reactions of 3-(5-Toco-
pheryDpropionic Acid
T. Rosenau*, W. D. Habicher, A. Potthast, P. Kosma

295 Syntetic studies Towards the B, C, D, E, Fragment of
Antobiotic CP44, 161
P. A. Allen ,M. A. Brimble, H. prabaharan
7 Facile Regio- and Stercocontrolled Synthesis of
Disubstituted Vinyl Sulfones via Transformation
Alkenylzirconocenes with Sulfonyl Chlorides
H. Duan, X. Huang*

19 irconium Tetrachloride (ZrC14) Catalyzed Highly
hemoselective and Efficient Transthioacetalization
Acetals
Firouzabadi*, N. Iranpoor*, B. Karimi

21 irconium Tetrachloride (ZrC14) Catalyzed Highly
hemoselective and Efficient Acetalization of
arbonyl Compounds
Firouzabadi,* N. Iranpoor,* B. Karimi

24 alladium(0)-Catalyzed Coupling Cyclization of
unctionalized Allenes with Hypervalent lodonium
alts
K. Kang,* T.-G Baik, A. N. Kulak

27 Toss-Coupling of Organostannanes with Organic
odides Catalyzed by Silica-Supported Poly[3-(2-
yanoethylsulfanyDpropylsiloxane palladium]
omplex Under Aqueous Medium
K. Kang,* T.-G Baik, S.-Y. Song

30 Simple and Efficient Method for the Preparation
ifl-Benzyloxy-5-hydroxynaphthalene
Becher, 0. A. Matthews, M. B. Nielsen, F. M. Raymo,
F. Stoddart*

299 beta-Tosylhydrazono Phosphonates in Organic
Synthesis. An Unambiguous Entry to Polysub-
stituted Pyrazoles
N. Almirante, A. Benicchio, A. Cerri, G, Fedrizzi, G. Marazzi
M. Santagostino*

303 A Novel Synthesis of4-Methyl-l,3-Dioxolane-4-
Carbaldehydes by Epoxidation of 5-Methyl-4H-l,3-
Dioxins and Acid-Catalyzed Rearrangement
C. Waltenbach, M. Maurer, H. Frauenrath*

307 Parallel Synthesis of Polyethylene Glycol Supported
Biaryl Benzimidazoles and Imidazopyridines
C. G Blettner, W. A. Konig, G. Ruhter, W. Stenzel, T, Schotten *

311 Iodine and its Interhalogen Compounds: Versatile
Reagents in Carbohydrate Chemistry IX. A Mild
and Selective Deprotection of tert-ButyIdimethylsily
(TBDMS) Ethers in the Presence of Various Protec-
ting Groups Using Iodine Monobromide
K.P. Ravindranathan Kartha*, R. A. Field

313 Convenient Synthesis of 2-Furylsugars
S. Jarosz*, M. Mach, S. Skora

315 Potassium Exchanged Zirconium Hydrogen Phos-
phate as Heterogeneous Catalyst in Cyanosilylation
of Carbonyl Compounds
M. Curini*, F. Epifano, M. C. Marcotullio, 0. Rosati, M. Rossi

333 Asymmetric Biomimetic Oxidations of Phenols:
Enantioselective Synthesis of (+)- and (-)-Dehydro-
diconiferyl Alcohol
P. RuiTimakko,* G. Brunow, M. Orlandi, B. Rindone

336 Intramolecular Tishchenko Reactions of Protected
Hexos-5-uloses: a Novel and Efficient Synthesis of L-
Idose and L-Altrose
M. Adinolfi, G. Barone, F. De Lorenzo, A. ladonisi*

339 Efficient Simultaneous Closure of Polysubstituted 1-
Aminopyrrole Rings Spaced by a Variable Number
of Methylene Groups
0. A. Attanasi, L. De Crescentini, P. Filippone,* F. R. Perrulli,
S. Santeusanio

342 Synthesis of5,5'-Bisfunctionalized 2,2': 6',2"-Ter-
pyridines using Functionalized Pyridine Building
Blocks
U. S. Schubert,* C. Eschbaumer, C. H. Weidi

345 Carbon-Carbon Bond Forming Reactions In Super-
critical Carbon Dioxide in the Presence of a
Supported Palladium Catalyst
S. Cacchi,* G. Fabrizi, F. Gasparrini, C. Villani

348 Dipolar [3+2] Cycloaddition Reactions with Planar
Chiral Arene Tricarbonyl Chromium Complexes:
Synthesis of Enantiopure T^isubstituted Pyrrolidines
B. Schnell, G Bernardinelli, E. P. KUndig*

351 High Pressure Synthesis of New Silicon Containing
Heteroatom Analogues of Fused Norbornenes
S. 1. Kirin, F.-G Klarner, M. Eckert-Maksic*

354 Titanocene(ll)-Promoted Cyclization of Unsaturated
Thioacetals
T. FujiwaTa, T. Takeda*

357 Selective Deprotection of Triethylsilyl Group in the
Presence of f-ButyIdimethylsilyl Group with MCM-
41/MeOH Heterogeneous System
A. ltoh, T. Kodama, Y. Masaki*

360 (S,S)-4,4'-Bis(3-hydroxy-estra-l,3,5(10),6,8-
pentaene): An Efficient Ligand for the Catalytic
Asymmetric Oxidation of Sulfides to Sulfoxides
C. Bolm*, 0. A. G Dabard

363 Nafion-H Catalyzed Isomerization of Glycidic to alpha-
Hydroxy-beta, gama-unsaturated Esters: Application in the
Synthesis of a Trifluoromethylated Vinylic Epoxide
M. Hachoumy, T. Mathew, E. C. Tongco, Y. D. Vankar,
G K. S. Prakash,* G A. Olah*

366 Discovery of New Multi Component Reactions with
Combinatorial Methods
L. Weber, K. Illgen, M. Almstetter

Spotlight 375
Errata 376

_______________________________________

SYNLETT
NO. 6, JUNE 1999


The Bis(enol triflate) Route to Dienediyne Models of 657
the Biradical Forming and DNA-Cleaving Natural
Product Neocarzinostatin Chromophore
R. Bruckner, J. Suffert



Pi Complexes with Annellated Cyclobutene Rings: 680
Bicyclo[3.2.0]heptadienyl Anion and Benzocycio-
butene as Ligands for Transition Metals
H. Butenschön



Synthetic Study ofPinnatoxin A: Intramolecular 692
Diels-Alder Approach to the AG-ring
A. Ishiwata, S. Sakamoto, T. Noda, M. Hirama



Synthetic Study of Pinnatoxin A: Intramolecular 695
Alkylation Approach to the G-ring
A. Nitta, A. Ishiwata, T. Noda, M. Hirama



Two Novel Strategies for the Construction of the 697
Core Acetal of the Zaragozic Acids
C. Taillefumier, M. Lakhrissi, Y. Chapleur





Synthesis of (+)-Azafagomme from D-xylose 701
B. V. Ernholt, l. B. Thomsen, K. B. Jensen, M. Bols


Formation of Four- to Six-Membered Carbocycles 705
by Tandem Brook Rearrangement-Intramolecular
Michael Reaction
K. Takeda, T. Tanaka


O-(Bcnzotriazol-l-yl)-N,N,N',N'-tetramethyl- 709
uronium Tetrafluoroborate (TBTU): A New Reagent
for the Cleavage of Tetrahydropyranyl, Silyl and
4,4_Dimethoxytrityl Ethers
K. S. Ramasamy, D. Averett



Ring A Functionalization of Terpenoids by the 713
Unusual Baeyer-Villiger Rearrangement of
Aliphatic Aldehydes
A. F. Barrero, E. J. Alvarez-Manzaneda, R. Alvarez-Manzaneda,
R. Chahboun, R. Meneses, M. Aparicio B.



Indium-Trichloride Mediated Synthesis of 717
4,4-Dichlorotetrahydropyrans
J. Yang, C.-J. Li



A Novel Enantioselective Synthesis of a-Azido 719
Ketones
D. Enders, D. Klein


A Stereoselective Synthetic Route to (E)-2-Aryl- 721
vinylphosphonates
P. Zhong, X. Huang, Z.-X. Xiong


Total Syntheses of Trichodenones A-C 723
Y. Usami, A. Numata


First Synthesis of 2,4-Bis(trifluoroacetyl)-6-dime- 725
thylaminopentafulvene by a Sequence of Reactions
Involving DMF, Trifluoroacetic Anhydride, and
Cyclopentadiene
C. Lamaire, L. Stella



A New Chiral Auxiliary Derived from (2 S)-Phenyl- 727
glycinol; an Access to Enantiomerically Pure
P-Amino Acids
C. Agami, S. Cheramy, L. Dechoux, C. Kadouri-Puchot



Efficient Synthesis of Aromatic sec-Amides from 729
Esters; Synthetic Utility of Bislithium Amides
T. Ooi, E. Tayama, M. Yamada, K. Maruoka


Synthesis and Reactions of a Hypervalent Iodine- 731
Benzyne Precursor Possessing an Ester Group
T. Kitamura, K. Wasai, M. Todaka, Y. Fujiwara



Organoselenium-induced Cyclization of 2-Alkenyl- 733
thiazolines to Functionalized y-Lactams
K. Terao, M. Kunishima, S. Tani


Eight-Membered Thiocycloether via Indium-Media- 735
ted Ring Enlargement
C.-J.UD.-L.Chen



Bis C-Glycosylated Diphenylmethanes for Stable 737
Glycoepitope Mimetics
T. Kuribayashi, S. Gohya, Y. Mizuno, M. Shimojima, K. lto,
S. Satoh


Asymmetric Synthesis of alfa -Substituted beta -Amino 741
Sulfones by aza-Michael Addition /alfa -Alkylation
D. Enders, S. F. Müller, G Raabe


Alkene Chemoselectivity in Ring-Closing Meta- 744
thesis; A Formal Synthesis of (-)-Periplanone-B
D. M. Hodgson, A. M. Foley, P. J. Lovell



alfa-Silyl Controlled Asymmetric Michael Additions of 747
Acyclic and Cyclic Ketones to Nitroalkenes
D. Enders, T. Otten



Preparation of a Rigid Macrocycle with Two 750
Exotopic Phenanthroline Binding Sites
M. Schmittel, H. Ammon



IVichloroacetimidate as an Efficient Protective 753
Group for Alcohols
B. Yu, H. Yu, Y. Hui, X. Han




One-pot Preparation of 2,6-Disubstituted 4-(Trifluo- 756
romethyDpyrimidines via the Tandem Cyclization,
Dehydration, and Oxidation Reaction of alfa , beta -Unsatu-
rated Trifluoromethyl Ketones Using POC(3)-Pyri-
dine-Silica Gel and MnO(2) Systems
K. Funabiki, H. Nakamura, M. Matsui, K. Shibata




Synthesis and Lipase-Catalyzed Enantiotope Selec- 759
tive Acetylation of2-Benzoyloxy-l,3-propanediol
V. Bodaia, L. Novaka, L. Poppe



Intramolecular Heck Cyclisation-beta -Alkoxy Elimi- 762
nation in Carbohydrate Chemistry. A Simple Route
to to Enantiopure Annelated Dioxatricyclic
Compounds
K. Bedjeguelal, V. Bolitt, D. Sinou




Enantioselective Synthesis of (R)- and (s) -Cizo- 765
lirtine; Application of Oxazaborolidine-Catalyzed
Asymmetric Borane Reduction to Azolyl Phenyl
Ketones
A. Torrens, J. A. Castrillo, A. Claparols, J. Redondo





A Novel Carbonylative Decomplexation of Alkyne- 768
Dicobalt Hexacarbonyls: Hydrocarbarnoylation of
Alkynes
T. Sugihara, Y. Okada, M. Yamaguchi, M. Nishizawa


The Intra- and Intermolecular Pauson-Khand 771
Reaction Promoted by Alkyl Methyl Sulfides
T. Sugihara, M. Yamada, M. Yamaguchi, M. Nishizawa



Synthesis of 3-Alkenyl-A3-cephems via Sequential 774
Reductive 1,2-Elimination/Addition/Cyclization in
an Alkenyltin/Copper(I ) Chloride/bpy System
H. Tanaka, Y. Tokumaru, S. Torii



Oxone®: A Convenient Reagent for the Oxidation of 777
Acetals
M. Curini, F. Epifano, M. C. Marcotullio, 0. Rosati




Synthetic Studies of Tedanolide. 4. Stereoselectiv 780
and Efficient Synthesis of the C13-C23 Part
T. Matsushima, B.-Z. Zheng, H. Maeda, N. Nakajima,
J.-i. Uenishi, O. Yonemitsu


Dynamic Control ofLigand Conformation: 783
Asymmetric Epoxidation Using Achiral
(Salen)manganese(III ) Complex
K. Miura, T. Katsuki




cis- and trans - (3-lndolyl)prolme Derivatives as 786
Conformationally Restricted Analogues of
Tryptophan
D. Damour, J.-P. Pulicani, M. Vuilhorgne, S. Mignani




Regiochemistry of the Reaction of 2-Acylcyclo- 789
hexanones with Trimethyl Orthoformate:
A Convenient One-Pot Method to Obtain
7,7-Dimethoxy Alkanoate Methyl Esters
M. A. P. Martins, G R Bastos, A. P. Sinhorin, A. F. C. Flores,
H. G Bonacorso, N. Zanatta



Towards a Synthesis of Glucidic Phosphoenol 792
Pyruvic Acid Derivatives
P. Coutrot, C. Grison, M. Tabyaoui, B. Tabyaoui, S. Dumarcay



Epoxidation of Electron Deficient Alkenes Using 795
tert-Butyl Hydroperoxide and 1,5,7-Triazabi-
cyclo[4.4.0]dec-5-ene and its Derivatives
T. Genski, G Macdonald, X. Wei, N. Lewis, R. J. K. Tayior



The Addition ofDiallylzinc to 5-Substituted 4,5- 798
Dihydroisoxazoles
F. J. F. Castro, M. M. Vila, P. R. Jenkins, M. L. Sharma, G Tustin,
J. Fawcett, D. R. Russell



Synthesis of Tetrasubstituted Ethylenic Compounds 801
from a gem -Trichloro-imidazole Derivative by
Electron Transfer Reactions
P. Vanelle, K. Benakli, L. Giraud, M. P. Crozet




Asymmetric Synthesis of Both Enantiomers of N- 804
Protected Epibatidine via Reductive Heck-Type
Hetarylation
J. C. Namyslo, D. E. Kaufmann



TEMPO-Induced Generation ofAlkyl Radicals from 807
ß-Alkylcatecholboranes
C.OIIivier,R.Chuard,P.Renaud




Rapid Parallel Synthesis of Benzimidazoles 810
C.-M. Yeh, C.-M. Sun



Novel Stereocontrolled Glycosidations of 2-Deoxy- 813
glucopyranosyl Fluoride Using a Heterogeneous
Solid Acid, Sulfated Zirconia (SO(4) ZrO(2)
K. Toshima, K.-i. Kasumi, S. Matsumura



Oxovanadium(IV) Complex-mediated Catalysis in 816
Mukaiyama-type Aidol Additions
C.-T. Chen, S.-W. Hon, S.-S. Weng




The Synthesis of a Thymine Containing E-Olefinic 819
Peptide Nucleic Acid (OPA) Monomer
C. D. Roberts, R. Schütz, C. J. Leumann




New Feature of Friedel-Craffcs Phosphonation of 822
Anisoles; Unexpected In Situ Methylphosphor-
ylation Reaction
G Baccolini, C. Boga


In Vitro Selected Oligonucleotides as Tools in 825
Organic Chemistry
A. Jaschkc, C. Frauendorf, F. Hausch


Spotlight 834

SYNLETT
NO. 7 , 1999



Recent Progress on the Ring Cleavage of Cyclic 1009
2-Nitro Ketones by External Nucleophiles
R. Ballini


Different Approaches to Mid-Valent, Paramagnetic
Half-Sandwich Complexes of the Heavier Group 6
Metals 1019
R. Poli


Titanocene(II)-Promoted Intramolecular 1029
Olefination of Thiol Esters: A New Route to
Substituted 2,3-Dihydrothiophenes
Md. A. Rahim, T. Fujiwara, T. Takeda


Novel Annelation Methodology for the Rapid and 1033
Efficient Construction of Bicycle [4.n.0] Alkanols
and Alkenones
I. E Markö, A. Ates

A Simple Convergent Method for the Construction 1037
of Fused Tri- and Tetracyclic Ethers
K. Fujiwara, K. Saka, D. Takaoka, A. Murai
Synthesis of Enantiopure C-Glycosides and Pseudo 1041
C-Glycosides. Lewis Acid Mediated Cleavage of
[3.3.1] Oxabicyclic Lactones
O. Gaertzen, A. M. Misske, P. Wolbers, H. M. R. Hoffmann


HBF(4) Catalyzed Mannich-Type Reaction in 1045
Aqueous Media
T. Akiyama, J. Takaya, H. Kagoshima


Why Do (R,R)- and (R,S)-(Salen)manganese(III) 1049
Complexes Show Different Substrate-Specificity?
The Role of an Apical Aqua Ligand
T. Punniyamurthy, R. Irie, T. Katsuki, M. Akita, Y. Moro-oka


A Convenient Method for the Preparation of N-Sub- 1053
stituted I-Acetonylaminocyclopropanes from Ace-
toacetic Ester Ethylene Acetal
M. V. Raiman, N. A. IVina, 0. G Kulinkovich


Stereoselective Synthesis of 1,1-Bimetalloalkenes of 1055
Tin and Selenium, Tin and Tellurium
C. P. Park, J. W. Sung, D. Y. Oh


Copper (1) Mediated Conjugate Addition of 1057
Grignard Reagents to 2-Oxoethylcyclohexenols.
A Versatile, Efficient and Diastereoselective
Route to anu, Z 6-Alkyl-2-trialkylsilyloxy-l-(2-tri-
methylsilyloxypropylid-l-ene)-cyclohexanes
V. Dambrin, M. Villieras, H. Amn, J. Lebreton, J. Villieras

Direct Aidol Reactions of Glyoxylic Acid Monohy- 1059
drate with Ketones
T.-R Loh, L.-L. Wei, L.-C. Feng


Novel Solid State Reduction of Organic Functional 1061
Groups on Solid Support (Merrif leides Resin)
S. Chandrasekhar, A. Raza, M. B. Padmaja


One Pot Deprotective Oxidation of O-Allyl Ethers 1063
Using 70% tert-Butyl Hydroperoxide and Catalytic
CrO(3)
S. Chandrasekhar, P. K. Mohanty, T. Ramachander


Reduction of Aromatic Nitro Compounds Using 1065
Samarium Metal in the Presence of a Catalytic
Amount of Iodine under Aqueous Media
L. Wang, L. Zhou, Y. Zhang


Nafion-H Catalysed Intramolecular Friedel-Crafts 1067
Acylation: Formation of Cyclic Ketones and Related
Heterocycles.
G A. Olah, T. Mathew, M. Famia, G K. S. Prakash

An Efficient Stereospecific Method for the Synthesis 1069
of 8-Aza-3-deazaguanine Nucleosides from Glycosyl
Azides
A. Stimac, I. Leban, J. Kobe
A Novel Oxidatively Removable Linker and Its 1074
Application to a-Selective Solid-Phase Oligo-
saccharide Synthesis on a Macroporous Polystyrene
Support
K. Fukase, Y. Nakai, K. Egusa, J. A. Porco, Jr., S. Kusumoto


Synthesis of 2-Substituted 3-Acylbenzo[b]furans via 1079
the Palladium Catalysed Carbonylative Cyclisation
of ortho-Hydroxytolans
H. Lütjens, R J. Scarnmells


Sequential Anionic 1,3 Ester Shifts and Intramolecu- 1082
lar Stille Couplings: A New Protocol for the Concise
Assembly of Functionalized Polycyclic Dienes
E. Piers, M. A. Romero, S. D. Walker


Generation and Reactions of Ammonium Ylides in 1085
Basic Two-Phase Systems: Convenient Synthesis of
Cyclopropanes, Oxiranes and Alkenes Substituted
with Electron-Withdrawing Groups
A. Jonczyk, A. Konarska


Dienediolates of a,P-Unsaturated Carboxylic 1088
Acids in Synthesis: A New Synthetic Method to
2-Pyridones
E. M. Brun, S. Gil, R. Mestres, M. Parra


A Concise Route to Novel I-Aryl and l-Pyridyl-2- 1091
Azabicyclo[2.1.1]hexanes
D. W. Piotrowski
Efficient 1,3-Asymmetric Inductions during 1094
Nucleophilic Additions to Imine and Iminium Ion
Derivatives
C. Agami, S. Comesse, C. Kadouri-Puchot, M. Lusinchi


Pd(0)-Mediated Cross Coupling of 2-lodoestradiol 1097
with Organozinc Bromides: A General Route to
the Synthesis of 2-Alkynyl, 2-Alkenyl and 2-Alkyle-
stradiol Analogs
A. K. Mohanakrishnan, M. Cushman


Efficient Synthesis of Quinazolin-4-ones and Axially 1100
Chiral 2,2'-Bis-quinazolin-4-ones by Reaction of
Anthranilic Acid Derived Nucleophiles with Oxalic
Acid-Bis(imidoyl)chlorides
J. Wuckelt, M. Doring, R. Bekkert, R Langer


Synthetic Study on Ecteinascidin 743 Starting from 1103
D-Glucose
A. Endo, T Kann, T. Fukuyama


Synthesis of Both Enantiomers of Phenyiglycine 1106
Using (-)-Sparteine
C. Barberis, N. Voyer


Regioselective Buta-l,3-dienylation ofAldehydes via 1109
Transmetallation of 2-Tributylstannylbuta-l,3-diene
M. Luo, Y. lwabuchi, S. Hatakeyama

Design and Efficient Synthesis of Novel DNA 1112
Interstrand Cross-Linking Agents: C2-Linked
Pyrrolo[2,l-c][l,4]benzodiazepine Dimers
B. S. P. Reddy, Y. Damayanthi, J. W. Lown


Macrocyclic Studies of EZ and ZZ 12-membered 1115
Aza Macrocycles;
Novel Molecular Rearrangement Observed.
E. Bourque, M. Grenon, S. Laliberte, P. Deslongchamps


Total Synthesis of the Multidrug-Resistance 1118
Reversing Agent Hapalosin
M. Haddad, C. Botuha, M. Larcheveque


Functionalization via Radical Cyclization of Cycio- 1121
hexenediol Derivatives Bound to Polystyrene
S. Berteina, A. De Mesmaeker, S. Wendeborn


A Novel Palladium-Catalysed Coupling Strategy for 1124
the Rapid Synthesis of Nucleic Acid Analogues
Bearing Modified Backbones
S. Abbas, C. J. Hayes


Synthesis ofEnantiomerically Pure Bicyclic Lactams 1127
N. Diedrichs, B. Westermann

Single Electron Transfer Diels-Alder Reaction of 1130
Fullerene with Danishefsky's Diene
K. Mikami, S. Matsumoto, Y. Okubo, T. Suenobu, S. Fukuzumi


Synthesis of a Stable Mimic for the Ring Closed 1133
Form of Gallein, Featuring a Novel One Pot Boron
Tribromide Mediated Intramolecular Cyclisation
Process
A. P. A. Crew, A. J. Lyons, N. P. Camp


Modified Trityl Ester Protecting Groups in Peptide 1136
Synthesis
B. Lohr, S. Orlich, H. Kunz


A Strategy Towards the Stereoselective Synthesis of 1139
5-Hydroxylysine
B. Lohr, S. Orlich, H. Kunz


On the Carbocyclization of W -Styrenylbenzyl- 1142
lithiums
A. Krief, B. Remade, W. Dumont


The Suzuki-Miyaura Cross-Coupling Reactions of 6- 1145
Halopurines with Boronic Acids Leading to 6-Aryl-
and 6-Alkenylpurines
M. Havelkova, M. Hocek, M. Oesnek, Dalimil Dvorak

Diethylzinc Mediated Radical Additions to Glyoxy- 1148
late Imines
M. P. Bertrand, L. Feray, R. Nouguier, P. Perfetti


Tetrahydrofuran a-Azido Esters: Precursors of 1151
Anomeric a-Amino Acid Monomers via Radical
Bromination
M. D. Smith, D. D. Long, A. Martfn, N. Campbell, Y. Bleriot,
G W. J. Fleet


A Novel Synthesis of Chiral Tetrahydroisoquinolines 1154
Employing Silyl Enol Ethers in the Presence of
Chiral Acyl Chlorides
T. ltoh, K. Nagata, M. Miyazaki, A. Ohsawa


Ru-Salen Catalyzed Asymmetric Epoxidation: Pho- 1157
toactivation of Catalytic Activity
T. Takeda, R. Inc, Y. Shinoda, T. Katsuki


Photo-controlled Lewis Acidity: Chiral (ON)Ru- 1160
Salen Catalyzed Hetero Diels-Alder Reaction and
Kinetic Resolution of Racemic Epoxides
J. Mihara, T. Hamada, T. Takeda, R. Irie, T. Katsuki


Chiral (ON)Ru-Salen Catalyzed Cyclopropanation: 1163
High Cis- and Enantioselectivity
T. Uchida, R. Irie, T. Katsuki

X-Ray Diffraction Analysis of Chiral (R,S)- 1166
(ON)Ru-Salen Complex: Unusual Unsymmetric
Conformation
T. Takeda, R. Irie, T. Katsuki


Synthetic Applications of Photoinduced Electron 1169
Transfer Decarboxylation Reactions
A. G Griesbeck, W. Krämer, M. Oelgemöller