TRANSFUSION (PHILADELPHIA)

VOL. 39, NO. 1, JANUARY 1999


EDITORIALS

1 Epitope mapping: three-dimensional insights from molecular biology
S. Dzik


6 Detecting alloantibodies in patients with autoantibodies
D.R. Branch and LD. Petz


IMMUNOHEMATOLOGY

11 Evaluation of methods for detecting alloantibodies underlying
warm autoantibodies
R.M. Legerand G. Garratty


17 Site-directed mutagenesis of the human D antigen: definition of
D epitopes on the sixth external domain of the D protein expressed
on K562 cells
W. Liu, J,S. Smythe, M.L Scott, J. W.Jones, D. Voak, and N.D. Avent


26 Clinical evaluation of a solid-phase test for red cell antibody screening
of pregnant women
A. Shanwell, S. Sallander, K. Bremme, and M. Westgren


32 NOR polyagglutination and St^ glycophorin in one family:
relation of NOR polyagglutination to terminal (x-galactose residues
and abnormal glycolipids
G. Kusnierz-Alejska, M. Duk, J.R. Storry, M.E. Reid, B. Wi^cek, H. Seyfried,
and E. Lisowska


TRANSPLANTATION

39 Mobilization of blood-derived stem and progenitor cells in normal
subjects by granulocyte-macrophage- and granulocyte-colony-stimulating
factors
T.A. Lane, A,D. Ho, A. Bashey, S. Peterson, D, Young, and P Law


48 Improved collection of mobilized CD34+ hematopoietic progenitor cells
by a novel automated leukapheresis system
F.Ravagnani, S. Siena, S. DeReys, M. Di Nicola, PNotti, R. Giardini,
M. Bregni, PMatteucci,A. M. Gianni, and G. Pellegris

HEMOSTASIS

56 Variability of prothrombin time and activated partial thromboplastin
time in the diagnosis of increased surgical bleeding
D. Murray, B. Pennell, andJ. Olson

BLOOD COMPONENTS

63 Effects of methylene blue-treated plasma on red cells and stored platelet
concentrates
P.L. Perrotta, L. Baril, C. Tead, J. Chapman, D. Dincecco, D.H. Buchholz,
and E. L Snyder


70 Long-term storage at -80"C of hematopoietic progenitor cells with
5-percent dimethyl sulfoxide as the sole cryoprotectant
A. Galmes, /. Besalduch, /. Bargay, A. Novo, M. Morey, J.M. Guerra,
and M.A. Duran


74 Improved removal of white cells with minimal platelet loss by filtration
of apheresis platelets during collection
S. Hoi me, M. Andres, N. Goer mar, and G.E Giordano


TRANSFUSION COMPLICATIONS

83 Prevalence of GB virus type C/hepatitis G virus RNA and of anti-E2 in
individuals at high or low risk for blood-borne or sexually transmitted
viruses: evidence of sexual and parenteral transmission
J. Lefrere, ERoudot-Thoraval, L. Morand-Joubert, Y.Brossard,
F.Parnet-Mathieu, M. Mariotti, EAgis, G. Rouet,J. Lerable, G. Lefevre,
R. Girot, andPLoiseau

95 Prevalence of GB virus type C/hepatitis G virus RNA
and anti-E2 among blood donors in Southeastern France
J.E Cantaloube, P Gallian, P Biagini, H. Attoui, J, Escher, J. -P Zappitelli,
Y. Delord, P de Micco, and X. de Lamballerie

BLOOD DONORS AND BLOOD COLLECTION

103 Prevalence of HLAsensitization in female apheresis donors
T.L Densmore, L. T. Goodnough, S, Ali, M, Dynis, and H. Chaplin

LETTERS TO THE EDITOR

107 Current status of solvent/detergent-treated frozen plasma, whole-blood
inline filtration, and Creutzfeldt-Jakob disease
W.R. Mayr and M. Kohler

107 Hypotensive reactions during transfusion: Is bradykinin the culprit?
R. W. Colman and C.E Scott

109 Variation in Lan expression
J.R. Storry and R. 0yen

110 Hemolysis and acute renal failure due to the administration of albumin
diluted in sterile water
L.R. Pierce, A. Games, f.S. Finlayson, F.Varricchio, and J.S. Epstein

112 CALENDAR

113 INSTRUCTIONS FOR AUTHORS


_______________________________________


TRANSFUSION (PHILADELPHIA)

VOL. 39, NO. 2, FEBRUARY 1999


EDITORIALS

120 Albumin—does the bell toll for thee?
J.J. Skillman

123 Public health, public trust, and public decision making:
making hepatitis C virus lookback work
J.PAuBuchon

BLOOD COMPONENTS

128 Viability and in vitro properties of AS-1 red cells
after gamma irradiation
G. Moroff, S. HolmeJ.RAuBuchon, W.A. Heaton, J.D. Sweeney,
and L.L. Friedman

135 Quality assessment of platelet concentrates supplemented with
second-messenger effectors
J. Rivera, M.L. Lozano,J. Corral, Connor, R. Gonzdlez-Conejero, PFerrer,
L. Currie, and V. Vicente


144 Preparation of autologous platelets for the ophthalmologic treatment
of macular holes
S. Gehring, H. Hoerauf, H. Laqua, H. Kirchner, and H. KlUter

149 Measurement of circulating red cell volume using biotin-labeled red
cells: validation against (51)Cr-labeled red cells
DM. Mock, G.L Lankford,J.A. Widness, L.KBiirmeisler, D. Kahn,
and R.G. Strauss

156 Measurement of red cell survival using biotin-labeled red cells:
validation against (51)Cr-labeled red cells
DM. Mock, G.L. Lankford,J.A. Widness, L.F.Burmeister, D. Kahn,
and R.G.Strauss

IMMUNOHEMATOLOGY
163 Biotinylation modifies red cell antigens
H. Cowley, U. Wojda, KM. Cipolone,J.L. Procter, D.F.Stroncek,
and J .L. Miller

169 Male fetuses are particularly affected by maternal alloimmunization
to D antigen
B. Ulm, G. Svolba, M.R. Ulm, G. Bernaschek, and S. Panzer


BLOOD DONORS AND BLOOD COLLECITON

174 Preoperative autologous blood donation by 1073 elderly patients
undergoing elective surgery: a safe and effective practice
G. Gandini, M. Franchini, D. Bertuzzo, D. Olzer, I. Crocco, M. De Gironcoli,
and G. Aprili

TRANSPLANTATION

179 ABO incompatibility as an adverse risk factor for survival after
allogeneic bone marrow transplantation
R.J. Benjamin, S. McGurk, M.S. Ralston, W.H. Churchill, andJ.H. Antin

TRANSFUSION COMPLICATIONS

188 Transfusion-acquired hepatitis C: the Danish lookback experience
P.B. Christensen, K. Groenb^k, H.B. Krarup, and The Danish HCV
[hepatitis C virus] Lookback Group

194 Targeted hepatitis C lookback: Quebec, Canada
A. Long, G. Spurll, H. Demers, and M. Goldman

201 Lack of difference in cytomegalovirus transmission via the transfusion
of filtered-irradiated and nonfiltered-irradiated blood to newborn
infants in an endemic area
H. Ohto, N. Ujiie, and K. Hirai

206 Predictive value of past and current screening tests for syphilis in blood
donors: changing from a rapid plasma reagin test to an automated
specific treponemal test for screening
J. Aberle- Grasse, S.L. Orton, E. Notari IV, L.P Layug, R. G. Cable, S. Badon,
M.A. Popousky, AJ. Grindon, B.A. Lenes, andA.E. Williams

212 GB virus type C infection in patients treated for childhood acute
lymphoblastic leukemia
M. Aricb, M. Bissolati, G. Bossi, M. Asti, A Cerino, D. Caselli, A. Ricci,
C. Klersy, E. Silini, and M. U. Mondelli

REVIEW

218 Two-unit red cell apheresis and its potential advantages over traditional
whole-blood donation
P.A. Shi and P.M. Ness

LETTERS TO THE EDITOR

226 Potential effect of hemoglobin solutions on blood components
P. Menu, A Caron, B. Faiure-Fiorina, and J.-F-EStoltz, PhD

228 CALENDAR

_______________________________________


TRANSFUSION (PHILADELPHIA)

VOL. 39, NO. 3, MARCH 1999


EDITORIAL

229 Antibody screening: elimination of another piece of the test
P.D.Issitt

TRANSFUSION COMPLICATIONS
231 A randomized controlled trial comparing plasma removal with
white cell reduction to prevent reactions to platelets
N.M. Heddle, L Klama, R, Meyer, L Walker, L. Boshkov, R. Roberts,
S. Chambers, L Podlosky, P. O'Hoski, andM. Levine


BLOOD COMPONENTS

239 Elimination of cytokine production in stored platelet concentrate
aliquots by photochemical treatment with psoralen plus ultraviolet
Alight
D.J. Hei, /. Grass, L Lin, L Corash, and G. Cimino

249 Virus reduction in the preparation of intravenous immune globulin:
in vitro experiments
S. Chandra,J.E. Cavanaugh, CM. Lin, C. Pierre-Jerome, N. Yerram,
R. Weeks, E. Flanigan, andF. Feldman

258 Effect of recombinant human megakaryocyte growth and development
factor coupled with polyethylene glycol on the platelet storage lesion
E. Snyder, P. Perrotta, H. Rinder, L Baril,f. Nichol, andD. Gilligan

265 Six filters for the removal of white cells from red cell concentrates,
evaluated at 4°C and/or at room temperature
P.F. van derMeer, R.N.L Pietersz,J. T. Nelis, B. Hinloopen, WJA. Dekker,
and H.W.Reesink

271 Greater increase in cytokine concentration after salvage with filtered
whole blood than with washed red cells, but no difference in
postoperative hemoglobin recovery
A. Avail, M. Hyllner, J.P, Bengtson, L Carlsson, and A. Bengtsson

277 Alteration of red cell aggregability and shape during blood storage
T. Hovav, S. Yedgar, N. Manny, and G. Barshtein

TRANSFUSION PRACTICE

282 Frequency of immediate adverse effects associated with therapeutic
apheresis
B.C. McLeod, L Sniecinski, D. Ciavarella, H. Owen, T.H. Price, MJ. Randels,
and J.W. Smith


289 Hydroxyethyl starch reduces the chemotaxis of white cells through
endothelial cell monolayers
R. Hofbauer, D. Moser, S, Homykewycz, M. Frass, andS. Kapiotis

IMMUNOHEMATOLOGY

295 Revisiting the issue: can the reading for serologic reactivity following
37"C incubation be omitted?
W.J.Judd, D.R. Fullen, E.A. Sterner, R.D. Davenport, andP.C. Knafl

300 Evaluation of the gel system for ABO grouping and D typing
M.M. LangstonJ.L Procter, KM. Cipolone, andD.F. Stroncek

306 Ceftizoxime-induced hemolysis due to immune complexes:
case report and determination of the epitope
responsible for immune complex-mediated hemolysis
T. Endoh, A Yagihashi, M. Sasaki, andN. Watanabe

BLOOD DONORS AND BLOOD COLLECTION

310 Trypanosoma cruzi in a low- to moderate-risk blood donor population:
seroprevalence and possible congenital transmission
D.A. Leiby, M,H. Fucci, andRJ. Stump f

316 A case-controlled multicenter study ofvasovagal reactions in blood
donors: influence of sex, age, donation status, weight, blood pressure,
and pulse
J.J. Trouern-Trend, R.G. Cable, SJ. Badon, B.H. Newman,
and M.A.Popousky

REVIEW

321 Platelet growth factors: potential impact on transfusion medicine
D.J. KuterJ. Cebon, L.A. Harker, L.D. Petz, andJ. McCullough

LETTERS TO THE EDITOR

333 Effect of transfusion on lipid peroxidation products in the plasma
of thalassemic patients
G.D. Sher, WJ. Bart fay, P.P. Liu, andD.C. Lehotay

334 Peripheral blood progenitor cell collections in children
R. Moog andN. Muller

335 Failure of third-generation recombinant immunoblot assay to detect
hepatitis C virus core antibodies
H. Hennig, H. Kirchner, and H. Klilter, MD

336 Hepatitis G virus or hepatitis GB virus type C infection in
thalassemic patients
V. Papaevangelou, E. Spanou, C. Kattamis, andS. Hadziyannis

338 BOOK REVIEW

340 CALENDAR


 

_______________________________________


TRANSFUSHION ( PHILADELPHIA)
VOL. 39, NO. 6, JUNE 1999

COMMENTARY

549 Blood from patients with hereditary hemochromatosis—a wasted
resource?
G. Jeffrey and P.C. Adams

551 Hemochromatosis and blood donors: a perspective
R.A. Sacher

BLOOD DONORS AND BLOOD COLLECTION

555 Aliogeneic blood progenitor cell collection in normal donors after
mobilization with Filgrastim: the M.D. Anderson Cancer Center experience
P.Anderlini, M. Donate), K.-W. Chan, Y.O. Huh,A.P. Gee, MJ. Lauppe,
R.E. Champlin, andM. Korbling

561 The timing of granulocyte-colony-stimulating factor administration
after chemotherapy does not affect stem and progenitor cell apheresis
yield: a retrospective study of 65 cases
F. Lefrere, F.Audat, 0. Hermine, M. Cavazzana-Calvo, C. Belanger, B. Arnulf,
A. Bllzyn, and B. Varet

565 A new apheresis procedure for the preparation of high-quality red cells
and plasma
F. KnutsonJ. Rider, V. Franck, M.Joie, C.F. Hogman, andD. Pamphilon

572 White cell reduction during plateletpheresis: a comparison of three
blood cell separators
R. MoogandN. Müller

578 Hemochromatosis probands as blood donors
J.C. Barton, AJ. Grindon, N.H. Barton, andL.F. Bertoli

TRANSFUSION PRACTICE

586 Corrected count increment and percent platelet recovery as measures of
posttransfusion platelet response: problems and a solution
K.B. Davis, SJ. Slichter, andL Corash

IMMUNOHEMATOLOGY

593 Fc gamma RIIIB polymorphism: evidence that NAI / NA2 and SH are located in
two closely linked loci and that the SH allele is linked to the NAI allele in
the Danish population
R. Steffensen, T. Gulen, K. Varming, andCJersild


599 Photodynamic sterilization of red cells and its effect on contaminating
white cells: viability and mechanism of cell death
A.C.LL Moor, A. vflJl der Veen, T.M.A.R. Dubbelman,]. VanSteueninck,
a fid A. Brand

608 Blood irradiation for intraoperative autotransfusion in cancer surgery:
demonstration of efficient elimination of contaminating tumor cells
E. Hansen, R. Knuec fiel, J. Alltneppen, and K. Taeger

616 Platelet membrane integrity during storage and activation
TJ. Reid, G. Esteban, M. Clear, andM. Gorogias

TRANSFUSION COMPLICATIONS
625 Transfusion ofbuffy coat-depleted blood components and risk of
postoperative infection in orthopedic patients
P. Innerilofer, C. Walleczek, G. Luz, P. Hobisch-Hagen,A. Benzer,
B. Stockt, G. Hessenberger, W. Nussbaumer, and W. Schobersberger

633 Evaluation of RNA and E2 antibodies in prospectively followed
recipients of hepatitis G virus-infected blood
S. Sauled.a,J.I. EstebanJ.M. Hernandez, H. Reesink, D. CastellaJ. Quer,
G. Hess, R. Esteban, and], Guardia

639 Human T-lymphotropic virus type I among blood donors from
Guadeloupe: donation, demographic, and biologic characteristics
F. Rollet, C. Foucher, M. Rabier, I, Gawronski, D. Taverne, B. Chancerel,
O. Gasman, andM. Strobel

EDUCATION AND ADMINISTRATION
645 Costof umbilical cord blood units released for transplantation
G. Sirchia, P. Rebnlla, S. Tibaldi, and L Lecchi

651 A survey of phlebotomy among persons with hemochromatosis
S.M. McUonnell.A.J. Grindon, B.L Preston, /.C. Barton, C.Q. Edwards,
and P.C. Adams

LETTERS TO THE EDITOR
657 Red cell transfusion outcome studies require a prospective, randomized
design
R.B. Weiskopf

660 Effectivenessofa highly sensitive chemiluminescent immunoassay in
screening for hepatitis B surface antigen in Japanese blood donors
S. Sekigachi, S. Sato, T. Kato, andH. Ikeda

661 Collection of mononuclear cells in the Spectra for the generation of
dendritic cells
A. Glaser. J Zingsem, R. Zimmermann, V. Weisbach, and R. Eckstein

662 Nomenclature ofgranulocyte alloantigens
J. Büx

664 CALENDAR

__________________________


TRANSFUSION
VOL. 39, NO. 7, JULY 1999


EDITORIALS

665 Transfusion-associated immunomodulation and universal white cell
reduction: are we putting the cart before the horse?
M.A. Blajchman

671 Selective therapeutic extraction of plasma constituents, revisited
A.A.Pmeda

TRANSFUSION PRACTICE
674 Clinical consequences of alterations in platelet transfusion dose:
a prospective, randomized, double-blind trial
T.R, KlumppJ.H. Herman, f.P. Gaughan, R.R. Russo, R.A. Christman,
S.L Goldberg, SJ.Ackerman, G.C. Bleecker, andK.F, Mangan

682 Clinical evaluation of a staphylococcal protein A immunoadsorption
system in the treatment of myasthenia gravis patients
W.B. Benny, DM C. Sutton, J. Oger, V. Bril, MJ. McAteer, and G. Rock

TRANSFUSION COMPLICTIONS

688 Redefining the HIV-infectious window period in the chimpanzee model:
evidence to suggest that viral nucleic acid testing can prevent
blood-borne transmission
K.K. Murthy, D.R, Henrard, J.W. Eichberg, K.E. Cobb, M.P. Busch, J.P. Allain,
and H.J.Alter

694 Risk of bacterial infection associated with allogeneic blood transfusion
among patients undergoing hip fracture repair
J.L. Carson, D. G. Altman, A. Duff, H. Noueck, M.P. Weinstein,
F.A. Sonnenberg, J.L Hudson, and G. Provenzano

701 Transfusion and postoperative pneumonia in coronary artery bypass
graft surgery: effect of the length of storage of transfused red cells
EC. VamvakasandJ.H. Carven

711 A recombinant peptide antigen line immunoassay optimized for the
confirmation of Chagas' disease
W.M.R. Oelemann, B.O.M. Vanderborght, G.C. Verissimo Da Costa,
M.G.M. Teixeira,J. Borges-Pereira,J.A.F. De Castro, J.R. Coura, E. Stoops,
F. Hulstaert, M. Zrein, andJ.M. Peralta

BLOOD COMPONENTS

718 The effect of unmodified or prestorage white cell-reduced allogeneic
red cell transfusions on the immune responsiveness in orthopedic
surgery patients
J.O. Bordin,A.K. Chiba, K.LL. Carvalho, E.T. Takata, R.P. Falcäo,
A.B. Garcia, I.A.S. Bördln, MM. Maciel, S.Andreoni, and]. Kerbauy


724 Effects of prestorage white cell reduction on platelet aggregate
formation and the activation state ofplatelets and plasma enzyme
systems
D.V.Devine, AJ. Bradley, E. Maurer, E Levin, S. Chahal, K. Sermno,
and M. l. C. Gyongyossy-lssa

735 Platelet surface p-selectin, platelet-granulocyte heterotypic aggregates,
and plasma-soluble p-selectin during plateletpheresis
M. R. Bamard, H. MacGregor, R. Mercier, G. Ragno, L.E. Pivacek,
H.B. Hechtman, A.D. Michelson, and C.R. Valeri

742 Biocompatibility of a new cell separator studied by flow cytometry:
analyses of platelet antigens during apheresis and storage
K. Gutensohn, A. Alisch, N. Crespeigne, B. Eifrig, and P.Kuehnl

748 Factor Vlll/von Willebrand factor complex in methylene blue-treated
fresh plasma
J.A. Aznar, R. Molina, andJ.M. Montoro

IMMUNOHEMATOLOGY
751 Complement receptor I red cell expression is not controlled by the ln(Lu) gene
J.M. Moulds and C. Shah

756 Immunoglobulin isotype identification in red cell antibodies using flow cytometry
W.R. Price, S.T.Johnson, andB.R. Curtis

763 Alloimmunization after blood transfusion in patients with hematologic
and oncologic diseases
H. Schonewille, H. L. Haak, and AM. vanZijl

772 Antibodies to private and public HLA class I epitopes in platelet recipients
R. Zimmermann, G. Wittmann,]. Zingsem, R. Blasczyk, V Weisbach,
and R. Eckstein

781 Rapid phenotyping of HPA-1 a using either diabody-based
hemagglutination or recombinant lgG I-based assays
N.A. Watkins, K.L. Armour, PA. Smethurst, PMetcalfe, M.L Scott,
D.L. Hughes, G.A. Smith, L.M. Williamson, M.R. Clark, andWH. Ouwehand

LETTERS TO THE EDITOR
790 Hemoglobin losses due to plateletpheresis
E. Castro, J.L. Bueno, L. Barea, andR. Gonzalez

790 GB virus type C/hepatitis G virus infection in French blood donors with
anti-NS5 isolated reactivities by recombinant immunoblot assay for
hepatitis C virus
S. LaPerche, A. -M. Courouce, J. -M. Lemaire, J. Coste, C. Defer,
andJ.-F. Cantaloube

792 CALENDAR

793 BOOK REVIEWS

_____________________________________



TRANSFUSION (PHILADELPHIA)

VOL. 39, NO. 8, AUGUST 1999


EDITORIAL

795 Can blood transfusion transmit disease-producing genes?
W.H. (Sunny) Dzik, and A. Okayama

EDUCATION AND ADMINISTRATION

801 A study of an educational intervention to decrease inappropriate
preoperative autologous blood donation: its effectiveness and the
effect on subsequent transfusion rates in elective hysterectomy
M.H. Kanter, D. van Maanen, K.H. Anders, F. Castro, W. Win My a, and K. Clark

808 The cost-effectiveness of autologous transfusion revisited: implications
of an increased risk of bacterial infection with allogeneic transfusion
nberg, P Gregory, R. Yorntovian, L.B. Russell, W. Tiemey, M. Kosmin, and
J.L Carson

TRANSPLANTATION

818 Inhibition of a secondary human alloimmune response via the soluble
active component of CD154 (CD40L) in severe combined immune-deficient
mice engrafted with human lymphocytes
A.H. Lazarus, A.R Crow,}. Freedman, VBlanchette, andB. Hannach

824 Delayed massive immune hemolysis mediated by minor ABO incompatibility
after allogeneic peripheral blood progenitor cell transplantation
J .-P Salmon, S. Michaux,J,-PHermanne, E. Baudoux, C. Gerard,
D. Sontag-Thull, G. Fillet, andY.Beguin

TRANSFUSION COMPLICATIONS

828 An investigation into the possibility of transmission of tick-borne
pathogens via blood transfusion
PM.Arguin.J. Singleton, L.D. Rotz, E. Marston, T.A. Treadwell, K. Slater,
M. Chamberland.A. Schwartz, L. Tengelsen.^G. Olson, andJ.E. Childs

834 Severe delayed hemolytic transfusion reaction secondary to anti-At^
K.L. Cash, T. Brown, L. Sausais, J. Uehlinger, andLJ. Reed

838 First two cases of immune hemolytic anemia associated with ceftizoxime
J.M. Sharnmo, B. Calhoun, A.M Mauer, P.C Hoffman, J.M. Baron, and B. W. Baron


845 Comparative evaluation of 14 immunoassays for detection of antibodies
to the human T-lymphotropic virus types I and II using panels of sera
from Sweden and West Africa
S. Andersson, R. Thorstensson, K. Godoy Ramirez, A. Krook, M. von Sydow,
EDias, and G. Biberfeld

IMMUNOHEMATOLOGY

852 Application of RHD and RHCE genotyping for correct blood group
determination in chronically transfused patients
T.J. Legler, S. W. Eber, M. Lakornek, R. Lynen, J.H. Maas, A. Pekrun,
M. Repas-Humpe, W. Schroter, and M. Kohler


856 Toward standardization of CD34+ cell enumeration: an international study
W.Dzik,I.Sniecinski,andJ.Fischer


864 Comparison of volumetric capillary cytometry with standard flow
cytometry for routine enumeration of CD34+ cells
E.Cabezudo,Querol,J.A. Cancelas, and J. Garcia

873 CD36 deficiency is frequent and can cause platelet immunization in Africans
K. Lee, B. Godeau, PFromont, A. Plonquet, N. Debili, D. Bachir,
D. Reuiron,J. Gourin, E. Femandez, E.Galacteros, andPBierling

BLOOD COMPONENTS

880 Fresh, liquid-preserved, and cryopreserved platelets:
adhesive surface receptors and membrane procoagulant activity
M.R. Bamard, H. MacGregor, G. Ragno, L.E. Pivacek, S.F.Khuri,
A.D. Michelson, and C.R, Valeri

BLOOD DONORS AND BLOOD COLLECTION

889 The influence of automated plateletpheresis on systemic levels of
hematopoietic growth factors
V.Weisbach, H. Friedlein, A. Glaser,J, Zingsern, R. Zimmermann,
and R. Eckstein


895 Plateletpheresis efficiency: a comparison of the Spectra LRS and
AMICUS separators
R. /. Benjamin, P. Rojas, S. Christmas, /. Neal, S. Broughton, C. Burgio,
B. Barren, and W.H. Churchill


900 Determination of reasons for cessation of participation in serial plasma-
pheresis programs
M.B. Rodell and M.L Lee

904 Absence of human T-lymphotropic virus type I tax sequences in a
population of normal blood donors in the Baltimore, MD/Washington,
DC, area: results from a multicenter study
E.P Cowan, GJ. Nemo, A.E. Williams, R.K. Alexander, A. Vallejo, LK. Hewlett,
R.B. Lal, C.S. Dezzutti, D. Gallahan, K. George, B.A. Pancake,
D. Zucker-Franklin, P.R. McCurdy, and E. Tabor

CONFERENCE REPORT
910 Autologous transfusion, 3 years on: What is new? What has happened?
J .-P Allain, R.LAkehurst, andJM. Hunter

LETTERS TO THE EDITOR

912 Summary of a Food and Drug Administration workshop on nucleic acid
testing to screen donations of blood and plasma for the hepatitis C virus
E .Tabor, L. Hewlett, M.-YWYu.M. Farshid, and .J. Epstein

913 Hepatitis C virus infection in blood donors in the People's Republic of China
X.L. Shi, Q.H. Pen, Z.Y.Zhu, DM. Qu, YJi, D.H. Peng, and S.Q. Ni

913 Clump formation in apheresis platelet concentrates
S. Nakajo, F.Hirayama, K. Niwa, M. Akino, T. Mitani, M. Chiba, K. Ikebuchi,
and S. Sekiguchi


916 CALENDAR

__________________________________


TRANSFUSION (PHILADELPHIA)

VOL. 39, NO. 9, SEPTEMBER 1999


EDITORIALS

917 The future of transfusion medicine
T.J. Greenwalt

920 New variant Creutzfeldt-Jakob disease and white cell reduction:
risk assessment and decision making in the absence of data
S. Kleinman

EDUCATION AND ADMINISTRATION

925 The cost-effectiveness of reducing donor exposures with single-donor
versus pooled random-donor platelets
I .Lopez-Plaza,J, Weissfeld,and D. J. Triulzi


933 Erythropoietin and preoperative autologous blood donation in the
prevention of hepatitis C infection: necessity or luxury?
M.-C. Woronoff-Lernsi, P. Arueux, S. Limat, P. Morel, C LePen, and]. - Y. Cahn

938 Cost-effectiveness of a limited-donor blood program for neonatal
red cell transfusions
P. Hilsenrath, J. NemechekJ.A. Wid'ness, D.G. Cordle, andR.G. Strauss

TRANSFUSION COMPLICATIONS

944 Transfusion-related acute lung injury due to granulocyte-agglutinating
antibody in a patient with paroxysmal nocturnal hemoglobinuria
B. ZupaAska, M. Uhrynowska, andL. Konopka

948 Hemolytic transfusion reaction due to anti-Tc(a)
MA Kolvalski, S.R. Pierce, R.L Edwards, S. Ethirajan, K Ryan, andM.P. Livergood


BLOOD COMPONENTS

951 Platelet concentrates prepared and stored under currently optimal
conditions: minor impact on platelet adhesive and cohesive functions
after storage
M. Lozano, E. Estebanell, J. Cid, M. Diaz-Ricart, R. Mazzara.A. Ordinas,
and G. Escolar

960 Quality and clinical response to transfusion of prestorage
white cell-reduced apheresis platelets prepared by use of an in-line
white cell-reduction system
M. Elfath, H. Tahhan, P. Mintz, L Dumont, P. WJutley, S. Sawyer, andD. McNeil


967 Reduction of blood loss byinfusion of human platelets in a rabbit kidney
injury model
C. Krishnamurti, P. Maglasang, andS.W. Rothwell



975 Coexpression of tissue factor and tissue factor pathway inhibitor by
human monocytes purified byleukapheresis and elutriation. Response
of nonadherent cells to lipopolysaccharide
P. Nguyen, M. Broussas, P. Cornillet-Lefebvre, and G. Potron


983 Granulocyte storage and antigen stability
H. Chun, K. Cipolone,J, Procter, andD,F. Stroncek

991 The viability of auto logo us human red cells stored in additive solution 5
and exposed to 25°C for 24 hours
T.J. Reid,J. G. Babcock, C.P. Derse-Anthony, H,R. Hill, LE. Lippert, andJ.R. Hess

TRANSFUSION PRACTICE

998 Comparison ofAdsol and CPDA-1 blood preservatives during simulated
massive resuscitation after hemorrhage in swine
D.H. Buchholz,J.F. Borgia, M. Ward, J.E. Miripol, and J.M. Simpson


IMMUNOHEMATOLOGY

1005 Evaluation of a panel of human monoclonal antibodies to D and
exploration of the synergistic effects of blending lgG3 and lgG3
antibodies on their in vitro biologic function
S.S. Armstrong-Fisher, M.C. McCann Carter, L Downing, R.H. Fraser,
G.E. Inglis, E.K. Allan, A Mackie, C.V. Prowse.J.G. Templeton, S.J. Thorpe,
and S.J. Urbaniak


1013 Molecular analysis of secretor type a(l,2)-fucosyltransferase gene
mutations in the Chinese and Thai populations
J.G. Chang, T. Y. Yang, T.C. Liu, T.P. Lin, CJ. Hu, M.C. Kao, NM. Wang,
F.J. Tsai, C. T. Peng, and C.H. Tsai

COMMITTEE REPORT

1018 Use of blood therapeutically drawn from hemochromatosis patients
L. Tan, M.K. Khan, and J. C. Hawk III, for the Council on Scientific Affairs,
American Medical Association

COMMENTARY

1027 Integrating the new generation of blood components into transfusion
practice
P.M. Ness


1031 What is a transfusion medicine specialist?
L. T. Goodnough

LETTERS TO THE EDITOR

1034 Immune tolerance in hemophiliacs: Can we at ford it? Is it worth it?
L.M. Aledort and the Baxter Previously Untreated Patient Study Group

1035 Absence of intrauterine transmission of TT virus
D. Prati, C. DeMattei, E. Parma, L. Lecchi, G. Sirchia, andB. Chen


1036 CALENDAR
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